Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5740
Gene Symbol: PTGIS
PTGIS 		Q16647 prostaglandin I2 synthase 53 0.617 0.654 1.2E-09 0.630 limited < 0.001 3 1 2001 2003
Entrez Id: 183
Gene Symbol: AGT
AGT 		P01019 angiotensinogen Enzyme modulator 632 0.367 0.923 5.0E-08 0.600 None 0.932 146 3 1988 2020
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1 		P30556 angiotensin II receptor type 1 G-protein coupled receptor 381 0.423 0.846 5.3E-04 0.600 None 0.941 50 7 1994 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		P29474 nitric oxide synthase 3 559 0.378 0.885 6.7E-07 0.600 None 0.917 34 6 1995 2018
Entrez Id: 118
Gene Symbol: ADD1
ADD1 		P35611 adducin 1 Cellular structure 58 0.612 0.615 0.99 0.400 None 0.944 36 4 1995 2017
Entrez Id: 2784
Gene Symbol: GNB3
GNB3 		P16520 G protein subunit beta 3 Enzyme 136 0.518 0.808 3.3E-11 0.400 None 0.909 33 2 1998 2017
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		P35228 nitric oxide synthase 2 572 0.364 0.923 4.0E-15 0.330 None 1.000 3 0 1997 2001
Entrez Id: 8490
Gene Symbol: RGS5
RGS5 		O15539 regulator of G protein signaling 5 Enzyme modulator 49 0.647 0.423 5.3E-04 0.320 None 1.000 2 1 2009 2015
Entrez Id: 1889
Gene Symbol: ECE1
ECE1 		P42892 endothelin converting enzyme 1 Enzyme 89 0.541 0.769 0.96 0.310 None 1.000 1 0 2007 2007
Entrez Id: 481
Gene Symbol: ATP1B1
ATP1B1 		P05026 ATPase Na+/K+ transporting subunit beta 1 Transporter 13 0.700 0.462 1.00 0.310 None 1.000 1 0 2009 2009
Entrez Id: 7369
Gene Symbol: UMOD
UMOD 		P07911 uromodulin 140 0.520 0.846 3.1E-17 0.110 None 1.000 1 0 2014 2014
Entrez Id: 5972
Gene Symbol: REN
REN 		P00797 renin Enzyme 668 0.370 0.923 2.4E-07 0.100 None 0.927 110 3 1986 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 979 0.328 0.923 1.0E-37 0.100 None 0.907 108 5 1992 2020
Entrez Id: 1585
Gene Symbol: CYP11B2
CYP11B2 		P19099 cytochrome P450 family 11 subfamily B member 2 100 0.553 0.615 7.1E-19 0.100 None 0.949 39 4 1995 2018
Entrez Id: 3291
Gene Symbol: HSD11B2
HSD11B2 		P80365 hydroxysteroid 11-beta dehydrogenase 2 Enzyme 125 0.532 0.808 0.12 0.100 None 0.778 18 3 1996 2017
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2 		P07550 adrenoceptor beta 2 G-protein coupled receptor 323 0.442 0.923 0.53 0.100 None 1.000 14 5 1989 2017
Entrez Id: 59272
Gene Symbol: ACE2
ACE2 		Q9BYF1 angiotensin I converting enzyme 2 Enzyme 238 0.477 0.769 1.00 0.100 None 0.929 14 9 2002 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 816 0.337 0.885 3.2E-10 0.100 None 0.909 11 3 2005 2018
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1 		P08588 adrenoceptor beta 1 G-protein coupled receptor 100 0.555 0.769 2.9E-06 0.100 None 0.900 10 2 2002 2018
Entrez Id: 65266
Gene Symbol: WNK4
WNK4 		Q96J92 WNK lysine deficient protein kinase 4 Kinase 29 0.644 0.538 6.9E-25 0.100 None 0.800 10 0 2003 2016
Entrez Id: 6559
Gene Symbol: SLC12A3
SLC12A3 		P55017 solute carrier family 12 member 3 Transporter 170 0.493 0.808 3.0E-32 0.100 None 0.900 10 6 2004 2015
Entrez Id: 101054525
Gene Symbol: PGR-AS1
PGR-AS1 		PGR antisense RNA 1 172 0.514 0.808 0.100 None 0.900 10 0 1998 2014
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		P05305 endothelin 1 Signaling 518 0.380 0.846 0.46 0.100 None 1.000 10 0 1995 2019
Entrez Id: 9197
Gene Symbol: SLC33A1
SLC33A1 		O00400 solute carrier family 33 member 1 Transporter 132 0.529 0.769 9.9E-05 0.090 None 0.889 9 0 1998 2014
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 563 0.374 0.885 5.6E-47 0.090 None 0.889 9 0 1998 2014