Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		P21802 fibroblast growth factor receptor 2 Kinase 345 0.380 0.808 1.00 0.630 None 0.750 3 0 2013 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.500 None 0.980 47 3 2007 2019
Entrez Id: 4921
Gene Symbol: DDR2
DDR2 		Q16832 discoidin domain receptor tyrosine kinase 2 Kinase 91 0.541 0.769 0.55 0.490 None 1.000 9 1 2011 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.430 None 1.000 3 0 2014 2019
Entrez Id: 1969
Gene Symbol: EPHA2
EPHA2 		P29317 EPH receptor A2 Kinase 171 0.501 0.731 1.1E-05 0.410 None 1.000 1 0 2010 2019
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		P11362 fibroblast growth factor receptor 1 Kinase 470 0.362 0.885 1.00 0.400 None 0.966 29 0 2010 2019
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R 		P08069 insulin like growth factor 1 receptor Kinase 422 0.399 0.885 0.97 0.320 None 1.000 2 0 2018 2018
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		P46531 notch receptor 1 581 0.369 0.885 1.00 0.310 None 1.000 1 0 2019 2019
Entrez Id: 5347
Gene Symbol: PLK1
PLK1 		P53350 polo like kinase 1 Kinase 249 0.467 0.808 0.98 0.310 None 1.000 1 0 2017 2017
Entrez Id: 7273
Gene Symbol: TTN
TTN 		Q8WZ42 titin Kinase 175 0.470 0.885 2.6E-96 0.310 None 1.000 1 0 2019 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.200 None 1.000 24 5 1994 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.200 None 1.000 14 0 2014 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.200 None 1.000 10 0 2000 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 888 0.319 0.846 1.00 0.160 None 1.000 6 1 2007 2019
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3 		P22607 fibroblast growth factor receptor 3 Kinase 377 0.391 0.846 1.6E-05 0.160 None 1.000 6 2 2013 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 739 0.357 0.885 3.6E-03 0.150 None 0.833 5 0 2010 2017
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 303 0.435 0.808 0.99 0.120 None 0.667 2 0 2007 2019
Entrez Id: 2033
Gene Symbol: EP300
EP300 		Q09472 E1A binding protein p300 148 0.459 0.846 1.00 0.110 None 1.000 1 0 2016 2017
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A 		P04439 major histocompatibility complex, class I, A 583 0.370 0.846 1.3E-03 0.110 None 1.000 1 0 2014 2017
Entrez Id: 3856
Gene Symbol: KRT8
KRT8 		P05787 keratin 8 109 0.517 0.654 2.4E-08 0.110 None 1.000 1 0 2016 2019
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L 		Q96KA5 CLPTM1 like Enzyme 81 0.551 0.654 4.4E-05 0.110 None 1.000 1 1 2014 2017
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7 		Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 237 0.465 0.808 1.00 0.110 None 1.000 1 0 2016 2019
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3 		P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 62 0.588 0.692 1.4E-07 0.110 None 1.000 1 0 2011 2017
Entrez Id: 9201
Gene Symbol: DCLK1
DCLK1 		O15075 doublecortin like kinase 1 Kinase 118 0.545 0.615 1.00 0.110 None 1.000 1 0 2017 2018
Entrez Id: 1548
Gene Symbol: CYP2A6
CYP2A6 		P11509 cytochrome P450 family 2 subfamily A member 6 90 0.556 0.731 5.4E-09 0.110 None 1.000 1 0 2015 2017