Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5925
Gene Symbol: RB1
RB1 		P06400 RB transcriptional corepressor 1 Nucleic acid binding 220 0.444 0.885 1.00 0.720 None 1.000 2 0 2012 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.700 None 0.960 94 4 1990 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.500 None 0.923 11 0 1998 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.400 None 0.985 66 7 1990 2019
Entrez Id: 429
Gene Symbol: ASCL1
ASCL1 		P50553 achaete-scute family bHLH transcription factor 1 Transcription factor 95 0.552 0.692 0.68 0.400 None 1.000 36 0 1997 2020
Entrez Id: 3815
Gene Symbol: KIT
KIT 		P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 627 0.366 0.808 0.98 0.400 None 0.857 28 2 1991 2018
Entrez Id: 4610
Gene Symbol: MYCL
MYCL 		P12524 MYCL proto-oncogene, bHLH transcription factor Transcription factor 70 0.599 0.731 0.12 0.400 None 1.000 17 0 1987 2017
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4 		P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 237 0.450 0.885 1.00 0.400 None 1.000 15 0 2008 2019
Entrez Id: 3642
Gene Symbol: INSM1
INSM1 		Q01101 INSM transcriptional repressor 1 85 0.584 0.654 0.27 0.400 None 1.000 12 0 2006 2019
Entrez Id: 6657
Gene Symbol: SOX2
SOX2 		P48431 SRY-box transcription factor 2 Transcription factor 421 0.405 0.808 0.71 0.400 None 1.000 10 0 2000 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1011 0.311 0.962 0.98 0.390 None 1.000 9 0 2002 2019
Entrez Id: 551
Gene Symbol: AVP
AVP 		P01185 arginine vasopressin Signaling 378 0.437 0.846 7.4E-02 0.390 None 1.000 9 0 1987 2017
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		P11362 fibroblast growth factor receptor 1 Kinase 470 0.362 0.885 1.00 0.380 None 1.000 8 0 2012 2019
Entrez Id: 1993
Gene Symbol: ELAVL2
ELAVL2 		Q12926 ELAV like RNA binding protein 2 197 0.486 0.808 1.00 0.350 None 1.000 4 0 1996 2012
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP 		Q92793 CREB binding protein 277 0.428 0.808 1.00 0.330 None 1.000 3 0 2012 2019
Entrez Id: 84700
Gene Symbol: MYO18B
MYO18B 		Q8IUG5 myosin XVIIIB 27 0.628 0.615 1.0E-31 0.310 None 1.000 1 0 2002 2002
Entrez Id: 9353
Gene Symbol: SLIT2
SLIT2 		O94813 slit guidance ligand 2 159 0.511 0.769 1.00 0.310 None 1.000 1 0 2002 2012
Entrez Id: 8570
Gene Symbol: KHSRP
KHSRP 		Q92945 KH-type splicing regulatory protein Enzyme 148 0.526 0.846 1.00 0.310 None 1.000 1 0 2012 2016
Entrez Id: 121256
Gene Symbol: TMEM132D
TMEM132D 		Q14C87 transmembrane protein 132D 51 0.617 0.692 1.00 0.310 None 1.000 1 0 2012 2015
Entrez Id: 138474
Gene Symbol: TAF1L
TAF1L 		Q8IZX4 TATA-box binding protein associated factor 1 like Epigenetic regulator 5 0.839 0.154 0.96 0.310 None 1.000 1 0 2018 2018
Entrez Id: 1152
Gene Symbol: CKB
CKB 		P12277 creatine kinase B Kinase 54 0.608 0.615 0.22 0.310 None 0.500 1 0 1987 1988
Entrez Id: 9425
Gene Symbol: CDYL
CDYL 		Q9Y232 chromodomain Y like 13 0.760 0.308 1.00 0.310 None 1.000 1 0 2012 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.200 None 1.000 18 0 2002 2018
Entrez Id: 65975
Gene Symbol: STK33
STK33 		Q9BYT3 serine/threonine kinase 33 Kinase 38 0.666 0.346 2.2E-06 0.120 None 1.000 2 0 2017 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 459 0.379 0.846 2.4E-25 0.110 None 1.000 1 1 2017 2018