Source: INFERRED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 45 0.295 0.885 0.37 0.700 None 0.978 5 7 1990 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 382 0.320 0.923 7.9E-04 0.700 None 0.967 3 2 1990 2020
Entrez Id: 238
Gene Symbol: ALK
ALK 		Q9UM73 ALK receptor tyrosine kinase Kinase 22 0.396 0.846 3.2E-06 0.700 None 0.977 3 6 2008 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 342 0.319 0.846 1.00 0.700 None 1.000 3 14 2002 2019
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 72 0.435 0.808 0.99 0.700 None 1.000 1 2 2002 2019
Entrez Id: 6098
Gene Symbol: ROS1
ROS1 		P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 8 0.439 0.885 1.6E-72 0.700 None 1.000 1 1 2012 2020
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1 		Q02750 mitogen-activated protein kinase kinase 1 Kinase 144 0.439 0.846 0.90 0.650 None 0.857 2 6 2008 2019
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3 		P22607 fibroblast growth factor receptor 3 Kinase 307 0.391 0.846 1.6E-05 0.650 None 1.000 1 1 2013 2018
Entrez Id: 8626
Gene Symbol: TP63
TP63 		Q9H3D4 tumor protein p63 Transcription factor 266 0.362 0.769 1.00 0.500 None 0.929 5 5 2010 2017
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 35 0.328 0.923 6.0E-03 0.500 None 0.987 2 6 1989 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 191 0.303 0.885 1.00 0.500 None 1.000 2 10 2001 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 229 0.378 0.885 8.0E-02 0.500 None 0.923 1 9 1990 2016
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 24 0.344 0.923 1.00 0.500 None 1.000 1 3 2008 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 283 0.292 0.923 1.00 0.500 None 0.979 1 19 2010 2020
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L 		Q96KA5 CLPTM1 like Enzyme 34 0.551 0.654 4.4E-05 0.460 None 1.000 3 3 2009 2019
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		P21802 fibroblast growth factor receptor 2 Kinase 381 0.380 0.808 1.00 0.440 None 0.833 2 5 2008 2019
Entrez Id: 5894
Gene Symbol: RAF1
RAF1 		P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 147 0.418 0.885 0.85 0.430 None 1.000 1 1 2014 2016
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 216 0.390 0.808 0.49 0.420 None 1.000 1 2 2010 2016
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		Q92560 BRCA1 associated protein 1 Enzyme 43 0.454 0.731 0.99 0.420 None 0.667 0 0 2015 2017
Entrez Id: 369
Gene Symbol: ARAF
ARAF 		P10398 A-Raf proto-oncogene, serine/threonine kinase Kinase 3 0.619 0.654 0.96 0.410 None 1.000 2 2 2014 2016
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 187 0.373 0.962 1.00 0.410 None 1.000 2 1 2008 2018
Entrez Id: 6654
Gene Symbol: SOS1
SOS1 		Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 115 0.485 0.808 1.00 0.410 None 1.000 1 1 2016 2019
Entrez Id: 2044
Gene Symbol: EPHA5
EPHA5 		P54756 EPH receptor A5 Kinase 16 0.626 0.615 7.3E-05 0.400 None 1.000 1 1 2005 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 221 0.236 0.962 0.53 0.400 None 0.991 1 81 1992 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 85 0.300 0.885 0.39 0.200 None 0.933 1 4 1996 2016