Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 23 0.295 0.885 0.37 0.500 None 1.000 2 1 1988 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 84 0.236 0.962 0.53 0.200 None 0.985 1 67 1990 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 85 0.292 0.923 1.00 0.200 None 0.952 1 8 2006 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 22 0.300 0.885 0.39 0.200 None 0.957 1 1 1994 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 70 0.303 0.885 1.00 0.200 None 1.000 1 4 2002 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 23 0.328 0.923 6.0E-03 0.200 None 1.000 1 1 1993 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 66 0.320 0.923 7.9E-04 0.170 None 1.000 1 1 1992 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 6 0.344 0.923 1.00 0.150 None 0.833 1 3 1994 2017
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 16 0.401 0.808 1.00 0.130 None 1.000 1 4 1996 2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 71 0.378 0.885 8.0E-02 0.130 None 1.000 1 2 1992 2016
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 18 0.465 0.808 1.00 0.120 None 1.000 1 4 2012 2018
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 82 0.380 0.808 1.00 0.110 None 1.000 1 3 2009 2016
Entrez Id: 100270680
Gene Symbol: CASC11
CASC11
cancer susceptibility 11 6 0.641 0.577 0.110 None 1.000 1 3 2016 2019
Entrez Id: 100507500
Gene Symbol: EGFR-AS1
EGFR-AS1
EGFR antisense RNA 1 5 0.722 0.192 0.100 None 1.000 2 1 2006 2014
Entrez Id: 387
Gene Symbol: RHOA
RHOA
P61586 ras homolog family member A Enzyme modulator 7 0.502 0.808 0.60 0.100 None 1.000 1 2 2016 2016
Entrez Id: 2033
Gene Symbol: EP300
EP300
Q09472 E1A binding protein p300 28 0.459 0.846 1.00 0.100 None 1.000 1 1 2016 2016