Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2737
Gene Symbol: GLI3
GLI3 		P10071 GLI family zinc finger 3 187 0.436 0.846 1.00 0.700 strong 1.000 21 1 1999 2019
Entrez Id: 9786
Gene Symbol: KIAA0586
KIAA0586 		Q9BVV6 KIAA0586 10 0.565 0.731 5.1E-16 0.510 None 1.000 1 0 2004 2015
Entrez Id: 3239
Gene Symbol: HOXD13
HOXD13 		P35453 homeobox D13 160 0.483 0.808 8.6E-03 0.450 strong 0.833 5 0 1995 2017
Entrez Id: 64327
Gene Symbol: LMBR1
LMBR1 		Q8WVP7 limb development membrane protein 1 Receptor 18 0.619 0.308 1.3E-08 0.440 strong 1.000 4 0 2001 2017
Entrez Id: 8195
Gene Symbol: MKKS
MKKS 		Q9NPJ1 McKusick-Kaufman syndrome 52 0.566 0.692 2.1E-09 0.430 strong 1.000 3 1 2002 2016
Entrez Id: 79659
Gene Symbol: DYNC2H1
DYNC2H1 		Q8NCM8 dynein cytoplasmic 2 heavy chain 1 Enzyme 27 0.555 0.731 1.1E-44 0.430 None 1.000 3 0 2012 2018
Entrez Id: 2736
Gene Symbol: GLI2
GLI2 		P10070 GLI family zinc finger 2 257 0.446 0.846 0.97 0.430 strong 1.000 3 0 2003 2019
Entrez Id: 54903
Gene Symbol: MKS1
MKS1 		Q9NXB0 MKS transition zone complex subunit 1 Extracellular structure 64 0.505 0.769 3.4E-16 0.430 None 1.000 2 0 2002 2013
Entrez Id: 727857
Gene Symbol: BHLHA9
BHLHA9 		Q7RTU4 basic helix-loop-helix family member a9 19 0.644 0.269 0.30 0.420 strong 1.000 2 0 2012 2019
Entrez Id: 583
Gene Symbol: BBS2
BBS2 		Q9BXC9 Bardet-Biedl syndrome 2 56 0.565 0.654 1.0E-17 0.420 strong 1.000 2 0 2005 2011
Entrez Id: 79738
Gene Symbol: BBS10
BBS10 		Q8TAM1 Bardet-Biedl syndrome 10 9 0.644 0.538 1.7E-12 0.410 strong 1.000 1 0 2010 2010
Entrez Id: 585
Gene Symbol: BBS4
BBS4 		Q96RK4 Bardet-Biedl syndrome 4 17 0.647 0.615 1.5E-16 0.410 strong 1.000 1 0 1998 1998
Entrez Id: 27077
Gene Symbol: B9D1
B9D1 		Q9UPM9 B9 domain containing 1 Extracellular structure 9 0.572 0.692 2.8E-03 0.410 limited 1.000 1 0 2011 2014
Entrez Id: 6469
Gene Symbol: SHH
SHH 		Q15465 sonic hedgehog signaling molecule 171 0.461 0.846 0.98 0.340 limited 1.000 4 0 1998 2017
Entrez Id: 5307
Gene Symbol: PITX1
PITX1 		P78337 paired like homeodomain 1 92 0.561 0.654 0.88 0.330 strong 1.000 3 0 2012 2019
Entrez Id: 374654
Gene Symbol: KIF7
KIF7 		Q2M1P5 kinesin family member 7 30 0.528 0.731 2.3E-22 0.320 None 1.000 2 0 2011 2019
Entrez Id: 55112
Gene Symbol: WDR60
WDR60 		Q8WVS4 WD repeat domain 60 Cellular structure 5 0.592 0.654 4.3E-12 0.320 strong 1.000 2 0 2013 2018
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1 		Q15672 twist family bHLH transcription factor 1 Transcription factor 436 0.397 0.846 0.34 0.320 strong 1.000 2 0 1998 2018
Entrez Id: 56623
Gene Symbol: INPP5E
INPP5E 		Q9NRR6 inositol polyphosphate-5-phosphatase E 28 0.561 0.615 3.1E-03 0.320 None 1.000 2 0 2015 2017
Entrez Id: 652
Gene Symbol: BMP4
BMP4 		P12644 bone morphogenetic protein 4 Signaling 325 0.422 0.808 0.96 0.320 strong 1.000 2 1 2008 2011
Entrez Id: 91147
Gene Symbol: TMEM67
TMEM67 		Q5HYA8 transmembrane protein 67 35 0.512 0.769 2.1E-24 0.320 strong 1.000 1 0 2002 2007
Entrez Id: 54585
Gene Symbol: LZTFL1
LZTFL1 		Q9NQ48 leucine zipper transcription factor like 1 21 0.638 0.692 5.9E-02 0.310 strong 1.000 1 0 2014 2014
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.310 None 1.000 1 1 2007 2007
Entrez Id: 4750
Gene Symbol: NEK1
NEK1 		Q96PY6 NIMA related kinase 1 Kinase 25 0.575 0.769 1.9E-25 0.310 None 1.000 1 0 2011 2012
Entrez Id: 3190
Gene Symbol: HNRNPK
HNRNPK 		P61978 heterogeneous nuclear ribonucleoprotein K Enzyme 82 0.539 0.846 1.00 0.310 moderate 1.000 1 0 2009 2018