Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.400 None 1.000 10 0 2004 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.070 None 1.000 7 0 2011 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.060 None 1.000 6 0 2005 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.060 None 1.000 6 0 2005 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.060 None 1.000 6 0 2005 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.060 None 1.000 6 0 2005 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.240 None 1.000 5 0 2007 2014
Entrez Id: 83746
Gene Symbol: L3MBTL2
L3MBTL2
Q969R5 L3MBTL histone methyl-lysine binding protein 2 Nucleic acid binding 19 0.729 0.308 1.0E-08 0.040 None 1.000 4 0 1999 2019
Entrez Id: 26013
Gene Symbol: L3MBTL1
L3MBTL1
Q9Y468 L3MBTL histone methyl-lysine binding protein 1 Epigenetic regulator 22 0.729 0.269 1.5E-12 0.040 None 1.000 4 0 1999 2017
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.320 None 1.000 3 0 1996 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.030 None 1.000 3 0 2001 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.030 None 1.000 3 0 2010 2018
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
O43490 prominin 1 Transporter 477 0.410 0.846 1.9E-22 0.030 None 1.000 3 0 2006 2011
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.310 None 1.000 3 0 1996 2007
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box transcription factor 2 Transcription factor 503 0.405 0.808 0.71 0.320 None 0.667 3 0 2016 2018
Entrez Id: 51330
Gene Symbol: TNFRSF12A
TNFRSF12A
Q9NP84 TNF receptor superfamily member 12A 173 0.509 0.692 1.8E-02 0.020 None 1.000 2 0 2016 2018
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
P48735 isocitrate dehydrogenase (NADP(+)) 2 380 0.434 0.808 0.88 0.020 None 1.000 2 0 2010 2012
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.020 None 1.000 2 0 2018 2018
Entrez Id: 3099
Gene Symbol: HK2
HK2
P52789 hexokinase 2 Kinase 152 0.515 0.769 4.6E-03 0.020 None 1.000 2 0 2011 2017
Entrez Id: 3098
Gene Symbol: HK1
HK1
P19367 hexokinase 1 Kinase 161 0.542 0.731 0.91 0.020 None 1.000 2 0 2011 2017
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.020 None 1.000 2 0 2019 2019
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.310 None 1.000 2 0 1984 2012
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.310 None 1.000 2 0 2011 2017
Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
P25106 atypical chemokine receptor 3 G-protein coupled receptor 400 0.428 0.885 0.39 0.020 None 1.000 2 0 2015 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.310 None 1.000 2 0 2012 2018