Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.080 None 1.000 8 0 2004 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.030 None 1.000 3 0 2013 2018
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.010 None 1.000 1 0 2017 2017
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.010 None 1.000 1 0 2018 2018
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.040 None 1.000 4 0 2005 2019
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.100 None 0.875 24 2 1998 2020
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.020 None 1.000 2 0 2016 2018
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.010 None 1.000 1 0 2015 2015
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.040 None 1.000 4 0 2016 2019
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.010 None 1.000 1 0 2018 2018
Entrez Id: 8626
Gene Symbol: TP63
TP63
Q9H3D4 tumor protein p63 Transcription factor 816 0.362 0.769 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 726 0.363 0.846 0.060 None 1.000 6 0 2014 2018
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 737 0.364 0.962 3.5E-02 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 Signaling 724 0.365 0.962 1.4E-03 0.030 None 1.000 3 0 2010 2019
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
MT-CO2 pseudogene 12 703 0.368 0.962 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 355
Gene Symbol: FAS
FAS
P25445 Fas cell surface death receptor 754 0.372 0.923 0.81 0.010 None 1.000 1 2 2013 2013
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
P18510 interleukin 1 receptor antagonist 701 0.373 0.923 3.1E-02 0.030 None 1.000 3 0 2004 2010
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2
P29323 EPH receptor B2 Kinase 649 0.374 0.846 1.00 0.010 None 1.000 1 0 2019 2019