Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4763
Gene Symbol: NF1
NF1 		P21359 neurofibromin 1 Enzyme modulator 380 0.440 0.885 0.90 1.000 strong 0.941 68 12 1992 2019
Entrez Id: 4771
Gene Symbol: NF2
NF2 		P35240 neurofibromin 2 312 0.468 0.885 1.00 0.260 None 1.000 6 0 1997 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.100 None 1.000 10 0 1999 2018
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.100 None 0 1
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.080 None 1.000 8 0 1992 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.040 None 1.000 4 0 2005 2017
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.040 None 1.000 4 0 2007 2011
Entrez Id: 5058
Gene Symbol: PAK1
PAK1 		Q13153 p21 (RAC1) activated kinase 1 Kinase 221 0.494 0.808 1.3E-03 0.040 None 1.000 4 0 2004 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.040 None 0.750 4 2 2013 2017
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		P16234 platelet derived growth factor receptor alpha Kinase 452 0.415 0.808 1.00 0.030 None 1.000 3 0 2004 2006
Entrez Id: 4192
Gene Symbol: MDK
MDK 		P21741 midkine Signaling 209 0.494 0.808 0.23 0.030 None 1.000 3 0 1999 2002
Entrez Id: 4782
Gene Symbol: NFIC
NFIC 		P08651 nuclear factor I C Nucleic acid binding 63 0.626 0.654 9.1E-02 0.030 None 1.000 3 0 2004 2017
Entrez Id: 4803
Gene Symbol: NGF
NGF 		P01138 nerve growth factor Signaling 616 0.391 0.885 0.82 0.030 None 0.667 3 0 1980 1996
Entrez Id: 161742
Gene Symbol: SPRED1
SPRED1 		Q7Z699 sprouty related EVH1 domain containing 1 Receptor 58 0.644 0.577 0.97 0.030 None 0.667 3 0 2009 2010
Entrez Id: 6285
Gene Symbol: S100B
S100B 		P04271 S100 calcium binding protein B Calcium-binding protein 599 0.383 0.923 4.4E-02 0.030 None 0.333 3 0 2000 2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.030 None 0.667 3 0 2010 2016
Entrez Id: 5979
Gene Symbol: RET
RET 		P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.020 None 1.000 2 0 2002 2014
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.020 None 1.000 2 0 1999 2005
Entrez Id: 3815
Gene Symbol: KIT
KIT 		P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.020 None 1.000 2 0 2006 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.020 None 1.000 2 0 1999 2016
Entrez Id: 23512
Gene Symbol: SUZ12
SUZ12 		Q15022 SUZ12 polycomb repressive complex 2 subunit Nucleic acid binding 165 0.529 0.577 1.00 0.020 None 1.000 2 0 2014 2016
Entrez Id: 6662
Gene Symbol: SOX9
SOX9 		P48436 SRY-box transcription factor 9 466 0.419 0.846 1.00 0.020 None 1.000 2 0 2009 2011
Entrez Id: 6271
Gene Symbol: S100A1
S100A1 		P23297 S100 calcium binding protein A1 Calcium-binding protein 396 0.421 0.846 6.0E-03 0.020 None 0.500 2 0 2000 2000
Entrez Id: 2247
Gene Symbol: FGF2
FGF2 		P09038 fibroblast growth factor 2 Signaling 635 0.383 0.923 1.8E-02 0.020 None 1.000 2 0 1995 2002
Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A 		P11388 DNA topoisomerase II alpha 200 0.497 0.731 0.99 0.020 None 1.000 2 0 2003 2017