Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3664
Gene Symbol: IRF6
IRF6 		O14896 interferon regulatory factor 6 Transcription factor 151 0.486 0.769 1.00 0.900 strong 0.966 57 4 1999 2019
Entrez Id: 57822
Gene Symbol: GRHL3
GRHL3 		Q8TE85 grainyhead like transcription factor 3 Transcription factor 70 0.572 0.692 0.99 0.790 strong 0.889 9 1 2014 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.100 None 1.000 12 0 2017 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.100 None 1.000 10 0 2017 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1604 0.276 0.962 0.13 0.080 None 1.000 8 0 2017 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1030 0.321 0.962 4.6E-09 0.050 None 1.000 5 0 2004 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1533 0.281 0.923 5.9E-03 0.030 None 1.000 3 0 2017 2019
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		P09429 high mobility group box 1 Nucleic acid binding 671 0.368 0.923 0.82 0.020 None 1.000 2 0 2015 2017
Entrez Id: 3308
Gene Symbol: HSPA4
HSPA4 		P34932 heat shock protein family A (Hsp70) member 4 534 0.394 0.923 1.00 0.020 None 1.000 2 0 2019 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 1361 0.288 0.962 0.47 0.020 None 1.000 2 0 2018 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.020 None 1.000 2 0 2017 2018
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1173 0.310 0.962 2.7E-04 0.020 None 1.000 2 0 2017 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		Q16552 interleukin 17A 1034 0.324 0.923 4.3E-02 0.020 None 1.000 2 0 2017 2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 999 0.320 0.923 1.00 0.020 None 1.000 2 0 2018 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1011 0.311 0.962 0.98 0.020 None 1.000 2 0 2015 2018
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 698 0.358 0.885 2.9E-02 0.020 None 1.000 2 0 2018 2020
Entrez Id: 199
Gene Symbol: AIF1
AIF1 		P55008 allograft inflammatory factor 1 Calcium-binding protein 138 0.521 0.808 1.9E-06 0.020 None 1.000 2 0 2018 2018
Entrez Id: 60
Gene Symbol: ACTB
ACTB 		P60709 actin beta Cellular structure 957 0.325 0.923 0.99 0.020 None 1.000 2 0 2003 2017
Entrez Id: 1536
Gene Symbol: CYBB
CYBB 		P04839 cytochrome b-245 beta chain Ion channel 283 0.452 0.885 1.00 0.020 None 1.000 2 0 2019 2019
Entrez Id: 4807
Gene Symbol: NHLH1
NHLH1 		Q02575 nescient helix-loop-helix 1 Transcription factor 33 0.686 0.538 0.26 0.020 None 1.000 2 0 2001 2014
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12 		MT-CO2 pseudogene 12 703 0.368 0.962 0.020 None 1.000 2 0 2017 2018
Entrez Id: 4513
Gene Symbol: COX2
COX2 		P00403 cytochrome c oxidase subunit II Enzyme 762 0.352 0.962 0.020 None 1.000 2 0 2017 2018
Entrez Id: 50507
Gene Symbol: NOX4
NOX4 		Q9NPH5 NADPH oxidase 4 Enzyme 232 0.471 0.885 5.8E-20 0.010 None 1.000 1 0 2019 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1294 0.291 0.885 0.56 0.010 None 1.000 1 0 2018 2018
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 748 0.344 0.923 0.89 0.010 None 1.000 1 0 2017 2017