Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 816 0.337 0.885 3.2E-10 0.400 None 0.941 17 3 2000 2019
Entrez Id: 5457
Gene Symbol: POU4F1
POU4F1 		Q01851 POU class 4 homeobox 1 50 0.628 0.500 0.89 0.310 None 1.000 1 0 2010 2010
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.100 None 0.950 57 0 2003 2019
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10 		H3 histone pseudogene 10 769 0.350 0.846 0.100 None 0.938 32 0 2003 2019
Entrez Id: 57026
Gene Symbol: PDXP
PDXP 		Q96GD0 pyridoxal phosphatase Enzyme 142 0.533 0.731 0.26 0.100 None 0.966 29 1 1987 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.100 None 0.957 22 4 1993 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.100 None 1.000 10 1 2005 2019
Entrez Id: 3934
Gene Symbol: LCN2
LCN2 		P80188 lipocalin 2 Enzyme 463 0.405 0.885 1.1E-09 0.100 None 1.000 10 0 2010 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1533 0.281 0.923 5.9E-03 0.080 None 0.875 8 1 2008 2019
Entrez Id: 1471
Gene Symbol: CST3
CST3 		P01034 cystatin C 316 0.436 0.808 3.9E-03 0.070 None 1.000 7 0 2017 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 747 0.344 0.923 1.00 0.070 None 1.000 7 0 1991 2020
Entrez Id: 23541
Gene Symbol: SEC14L2
SEC14L2 		O76054 SEC14 like lipid binding 2 198 0.494 0.885 2.9E-08 0.070 None 1.000 7 0 2003 2013
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.060 None 1.000 6 1 2000 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1334 0.287 0.962 3.7E-02 0.060 None 1.000 6 0 1994 2009
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1294 0.291 0.885 0.56 0.060 None 0.833 6 0 1999 2015
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 1361 0.288 0.962 0.47 0.060 None 1.000 6 0 2009 2014
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 739 0.357 0.885 3.6E-03 0.050 None 1.000 5 0 2015 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.050 None 1.000 5 0 2005 2018
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1 		P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 356 0.407 0.885 8.9E-03 0.050 None 1.000 4 0 1995 2015
Entrez Id: 29126
Gene Symbol: CD274
CD274 		Q9NZQ7 CD274 molecule Receptor 990 0.324 0.923 1.9E-02 0.040 None 1.000 4 0 2013 2018
Entrez Id: 412
Gene Symbol: STS
STS 		P08842 steroid sulfatase Enzyme 342 0.431 0.846 0.81 0.040 None 1.000 4 0 2006 2013
Entrez Id: 213
Gene Symbol: ALB
ALB 		P02768 albumin Transporter 1089 0.317 0.962 0.64 0.040 None 1.000 4 0 2017 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		P09488 glutathione S-transferase mu 1 581 0.380 0.923 2.1E-03 0.040 None 0.750 4 0 1994 2011
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1030 0.321 0.962 4.6E-09 0.040 None 1.000 4 0 2010 2014
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		Q06546 GA binding protein transcription factor subunit alpha Transcription factor 630 0.379 0.885 1.00 0.040 None 1.000 4 0 2015 2019