Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.100 None 0.982 222 5 1989 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.100 None 0.990 102 0 2001 2020
Entrez Id: 238
Gene Symbol: ALK
ALK 		Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.100 None 0.957 69 0 2013 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.100 None 0.977 43 3 2011 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.100 None 0.950 20 0 2011 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274 		Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.100 None 0.889 18 0 2016 2019
Entrez Id: 6611
Gene Symbol: SMS
SMS 		P52788 spermine synthase 263 0.491 0.846 0.97 0.100 None 1.000 14 0 2016 2019
Entrez Id: 140821
Gene Symbol: RSS
RSS 		Russell Silver syndrome 103 0.578 0.692 0.100 None 1.000 14 0 2016 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.100 None 1.000 13 0 2012 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.100 None 1.000 12 0 1999 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.100 None 0.917 12 1 2012 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.100 None 1.000 10 0 2013 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.100 None 1.000 10 0 2013 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.100 None 1.000 10 0 2013 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.090 None 1.000 9 0 2000 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.090 None 1.000 9 0 1992 2019
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7 		O14733 mitogen-activated protein kinase kinase 7 Kinase 408 0.419 0.808 1.00 0.090 None 1.000 9 0 2014 2020
Entrez Id: 1950
Gene Symbol: EGF
EGF 		P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.080 None 1.000 8 0 1988 2019
Entrez Id: 5133
Gene Symbol: PDCD1
PDCD1 		Q15116 programmed cell death 1 497 0.402 0.846 0.42 0.070 None 1.000 7 0 2017 2019
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4 		P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 739 0.362 0.923 1.8E-02 0.070 None 1.000 7 0 2009 2019
Entrez Id: 6098
Gene Symbol: ROS1
ROS1 		P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 356 0.439 0.885 1.6E-72 0.070 None 1.000 7 0 2015 2020
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.070 None 1.000 7 0 1992 2015
Entrez Id: 5979
Gene Symbol: RET
RET 		P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.060 None 1.000 6 0 2015 2020
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3 		P21860 erb-b2 receptor tyrosine kinase 3 Kinase 318 0.448 0.808 1.7E-15 0.060 None 0.833 6 0 2009 2019
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.060 None 1.000 6 0 2013 2019