Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.090 None 0.889 9 2 1998 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.090 None 0.889 9 0 2011 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.070 None 1.000 7 0 2011 2020
Entrez Id: 29126
Gene Symbol: CD274
CD274 		Q9NZQ7 CD274 molecule Receptor 990 0.324 0.923 1.9E-02 0.060 None 1.000 6 0 2016 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.050 None 1.000 5 0 2018 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1087 0.320 0.885 1.4E-06 0.030 None 1.000 3 0 2018 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1011 0.311 0.962 0.98 0.030 None 1.000 3 0 2018 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1105 0.319 0.885 1.00 0.030 None 1.000 3 0 2018 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1077 0.322 0.885 1.00 0.030 None 1.000 3 0 2018 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 747 0.344 0.923 1.00 0.030 None 1.000 3 0 2012 2015
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 765 0.343 0.885 1.00 0.020 None 1.000 2 0 2015 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.020 None 1.000 2 0 2011 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 748 0.344 0.923 0.89 0.020 None 1.000 2 0 2014 2015
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 563 0.374 0.885 5.6E-47 0.010 None 1.000 1 0 2019 2019
Entrez Id: 65211
Gene Symbol: FRTS1
FRTS1 		Fanconi renotubular syndrome 69 0.599 0.654 0.010 None 1.000 1 0 2017 2017
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 888 0.319 0.846 1.00 0.010 None 1.000 1 0 2013 2013
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 459 0.379 0.846 2.4E-25 0.010 None 1.000 1 0 2019 2019
Entrez Id: 7057
Gene Symbol: THBS1
THBS1 		P07996 thrombospondin 1 448 0.407 0.885 1.00 0.010 None 1.000 1 0 2008 2008
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.010 None 1.000 1 0 2013 2013
Entrez Id: 79187
Gene Symbol: FSD1
FSD1 		Q9BTV5 fibronectin type III and SPRY domain containing 1 216 0.486 0.808 0.25 0.010 None 1.000 1 0 2016 2016
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A 		O14497 AT-rich interaction domain 1A 199 0.455 0.846 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 407000
Gene Symbol: MIR218-1
MIR218-1 		microRNA 218-1 8 0.722 0.231 0.010 None 1.000 1 0 2014 2014
Entrez Id: 406987
Gene Symbol: MIR204
MIR204 		microRNA 204 198 0.487 0.808 0.010 None 1.000 1 0 2016 2016
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1 		Q9NS23 Ras association domain family member 1 Enzyme modulator 378 0.420 0.808 4.9E-06 0.010 None 1.000 1 0 2013 2013
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10 		H3 histone pseudogene 10 769 0.350 0.846 0.010 None 1.000 1 0 2020 2020