Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.800 None 0.944 5 0 1989 2020
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 56 0.379 0.846 2.4E-25 0.800 None 0.833 1 1 2007 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.700 None 0.974 33 1 1990 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.600 None 0.983 7 0 1988 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 182 0.305 0.923 0.26 0.600 None 0.959 2 0 1994 2019
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1 		P09211 glutathione S-transferase pi 1 103 0.383 0.923 1.4E-02 0.600 None 0.839 1 0 1998 2019
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1 		P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 42 0.445 0.846 1.6E-07 0.600 None 0.947 1 0 2005 2019
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 39 0.435 0.808 0.99 0.600 None 1.000 1 1 2003 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.600 None 1.000 0 0 2002 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.600 None 0.967 0 0 2002 2019
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		Q92560 BRCA1 associated protein 1 Enzyme 108 0.454 0.731 0.99 0.550 None 1.000 1 0 2015 2019
Entrez Id: 7428
Gene Symbol: VHL
VHL 		P40337 von Hippel-Lindau tumor suppressor Enzyme 47 0.443 0.846 8.0E-02 0.530 None 1.000 1 2 1994 2005
Entrez Id: 5519
Gene Symbol: PPP2R1B
PPP2R1B 		P30154 protein phosphatase 2 scaffold subunit Abeta Enzyme 4 0.678 0.423 3.0E-15 0.520 None 1.000 0 3 1999 1999
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L 		Q96KA5 CLPTM1 like Enzyme 16 0.551 0.654 4.4E-05 0.500 None 0.978 3 2 2008 2019
Entrez Id: 8626
Gene Symbol: TP63
TP63 		Q9H3D4 tumor protein p63 Transcription factor 56 0.362 0.769 1.00 0.500 None 0.958 2 2 1999 2019
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3 		P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 39 0.588 0.692 1.4E-07 0.500 None 1.000 1 7 2008 2020
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5 		P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 53 0.593 0.577 2.1E-06 0.500 None 0.934 1 2 2008 2018
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4 		P30926 cholinergic receptor nicotinic beta 4 subunit Ion channel 33 0.644 0.423 0.14 0.500 None 1.000 1 13 2008 2018
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 47 0.460 0.808 1.2E-24 0.500 None 1.000 1 1 2000 2017
Entrez Id: 5002
Gene Symbol: SLC22A18
SLC22A18 		Q96BI1 solute carrier family 22 member 18 Transporter 13 0.595 0.692 6.5E-06 0.500 None 0 0
Entrez Id: 2237
Gene Symbol: FEN1
FEN1 		P39748 flap structure-specific endonuclease 1 Enzyme 4 0.550 0.731 4.8E-05 0.490 None 0.800 1 1 2003 2019
Entrez Id: 5893
Gene Symbol: RAD52
RAD52 		P43351 RAD52 homolog, DNA repair protein Nucleic acid binding 3 0.610 0.654 7.1E-11 0.450 None 1.000 1 1 2008 2018
Entrez Id: 1548
Gene Symbol: CYP2A6
CYP2A6 		P11509 cytochrome P450 family 2 subfamily A member 6 44 0.556 0.731 5.4E-09 0.400 None 0.868 6 0 1999 2018
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 120 0.378 0.885 8.0E-02 0.400 None 0.966 5 0 1986 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 115 0.300 0.885 0.39 0.400 None 0.953 4 0 1994 2020