Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3075
Gene Symbol: CFH
CFH 		P08603 complement factor H 393 0.441 0.885 0.86 0.500 None 0.961 486 85 2005 2019
Entrez Id: 387715
Gene Symbol: ARMS2
ARMS2 		P0C7Q2 age-related maculopathy susceptibility 2 36 0.670 0.308 5.2E-04 0.700 limited 0.951 182 8 2005 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.400 None 0.971 174 12 2000 2020
Entrez Id: 5654
Gene Symbol: HTRA1
HTRA1 		Q92743 HtrA serine peptidase 1 Enzyme 164 0.532 0.692 4.9E-04 0.500 limited 0.940 133 12 2006 2019
Entrez Id: 24
Gene Symbol: ABCA4
ABCA4 		P78363 ATP binding cassette subfamily A member 4 Transporter 227 0.493 0.769 5.3E-48 0.700 strong 0.957 70 7 1997 2019
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.500 None 0.902 61 4 1998 2019
Entrez Id: 629
Gene Symbol: CFB
CFB 		P00751 complement factor B 139 0.532 0.769 4.7E-16 0.700 limited 0.966 58 12 2006 2019
Entrez Id: 718
Gene Symbol: C3
C3 		P01024 complement C3 Enzyme modulator 343 0.445 0.885 0.90 0.700 limited 1.000 36 12 2007 2020
Entrez Id: 6120
Gene Symbol: RPE
RPE 		Q96AT9 ribulose-5-phosphate-3-epimerase 90 0.575 0.538 2.5E-04 0.100 None 0.970 33 2 2003 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.100 None 0.900 30 3 2006 2019
Entrez Id: 6785
Gene Symbol: ELOVL4
ELOVL4 		Q9GZR5 ELOVL fatty acid elongase 4 Enzyme 111 0.601 0.577 0.83 0.200 None 0.962 26 1 2001 2019
Entrez Id: 262
Gene Symbol: AMD1
AMD1 		P17707 adenosylmethionine decarboxylase 1 Enzyme 84 0.593 0.577 0.98 0.100 None 1.000 26 0 2007 2020
Entrez Id: 3426
Gene Symbol: CFI
CFI 		P05156 complement factor I 133 0.569 0.731 3.5E-08 0.500 None 0.960 25 4 2009 2019
Entrez Id: 5362
Gene Symbol: PLXNA2
PLXNA2 		O75051 plexin A2 307 0.447 0.808 1.1E-06 0.100 None 1.000 24 1 2011 2020
Entrez Id: 263
Gene Symbol: AMD1P2
AMD1P2 		adenosylmethionine decarboxylase 1 pseudogene 2 71 0.608 0.538 0.100 None 1.000 24 0 2007 2020
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.100 None 0.957 23 1 2007 2019
Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1 		P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 310 0.457 0.885 6.1E-02 0.100 None 0.955 22 7 2004 2019
Entrez Id: 7078
Gene Symbol: TIMP3
TIMP3 		P35625 TIMP metallopeptidase inhibitor 3 Enzyme modulator 325 0.445 0.923 0.63 0.500 None 0.905 21 0 1997 2019
Entrez Id: 5961
Gene Symbol: PRPH2
PRPH2 		P23942 peripherin 2 152 0.551 0.500 0.12 0.200 None 1.000 21 3 1993 2019
Entrez Id: 5176
Gene Symbol: SERPINF1
SERPINF1 		P36955 serpin family F member 1 Enzyme modulator 294 0.460 0.846 7.8E-08 0.100 None 1.000 18 3 2001 2018
Entrez Id: 10878
Gene Symbol: CFHR3
CFHR3 		Q02985 complement factor H related 3 55 0.663 0.462 1.7E-11 0.500 moderate 1.000 17 2 2006 2019
Entrez Id: 3990
Gene Symbol: LIPC
LIPC 		P11150 lipase C, hepatic type Enzyme 120 0.585 0.654 3.3E-07 0.200 None 0.882 17 1 2010 2019
Entrez Id: 3078
Gene Symbol: CFHR1
CFHR1 		Q03591 complement factor H related 1 90 0.588 0.615 2.6E-08 0.500 moderate 1.000 16 4 2006 2017
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1 		O95477 ATP binding cassette subfamily A member 1 Transporter 291 0.467 0.846 1.5E-13 0.200 None 0.938 16 2 2005 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 16 0 2012 2020