Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 840
Gene Symbol: CASP7
CASP7
P55210 caspase 7 Enzyme 83 0.581 0.654 5.4E-05 0.010 None < 0.001 1 0 2013 2013
Entrez Id: 6041
Gene Symbol: RNASEL
RNASEL
Q05823 ribonuclease L Kinase 85 0.579 0.692 2.0E-10 0.010 None 1.000 1 0 2012 2012
Entrez Id: 5566
Gene Symbol: PRKACA
PRKACA
P17612 protein kinase cAMP-activated catalytic subunit alpha Kinase 88 0.606 0.692 0.97 0.010 None 1.000 1 0 2017 2017
Entrez Id: 55272
Gene Symbol: IMP3
IMP3
Q9NV31 IMP U3 small nucleolar ribonucleoprotein 3 Nucleic acid binding 97 0.566 0.462 1.5E-07 0.010 None 1.000 1 0 2019 2019
Entrez Id: 10551
Gene Symbol: AGR2
AGR2
O95994 anterior gradient 2, protein disulphide isomerase family member Enzyme 108 0.556 0.692 9.2E-08 0.010 None 1.000 1 0 2014 2014
Entrez Id: 1999
Gene Symbol: ELF3
ELF3
P78545 E74 like ETS transcription factor 3 Transcription factor 112 0.551 0.808 0.98 0.030 None 1.000 3 0 2016 2019
Entrez Id: 4594
Gene Symbol: MMUT
MMUT
P22033 methylmalonyl-CoA mutase Enzyme 147 0.534 0.731 1.7E-22 0.010 None 1.000 1 0 1998 1998
Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC
P98088 mucin 5AC, oligomeric mucus/gel-forming Enzyme modulator 224 0.483 0.808 1.0E-08 0.020 None 1.000 2 0 2006 2019
Entrez Id: 5371
Gene Symbol: PML
PML
P29590 promyelocytic leukemia 274 0.477 0.846 0.21 0.010 None 1.000 1 0 2009 2009
Entrez Id: 1045
Gene Symbol: CDX2
CDX2
Q99626 caudal type homeobox 2 Transcription factor 278 0.458 0.769 0.53 0.010 None 1.000 1 0 2019 2019
Entrez Id: 842
Gene Symbol: CASP9
CASP9
P55211 caspase 9 Enzyme 293 0.458 0.808 7.4E-06 0.010 None < 0.001 1 0 2013 2013
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 317 0.455 0.846 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 Kinase 318 0.448 0.808 1.7E-15 0.010 None 1.000 1 0 2018 2018
Entrez Id: 57534
Gene Symbol: MIB1
MIB1
Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 329 0.438 0.769 3.4E-88 0.010 None 1.000 1 0 1999 1999
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 340 0.461 0.808 0.15 0.010 None 1.000 1 0 2011 2011
Entrez Id: 4288
Gene Symbol: MKI67
MKI67
P46013 marker of proliferation Ki-67 351 0.431 0.808 1.3E-28 0.010 None 1.000 1 0 1999 1999
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 379 0.436 0.846 1.1E-17 0.010 None 1.000 1 2 2009 2009
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.020 None 1.000 2 0 2017 2017
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase Enzyme 439 0.425 0.923 2.3E-06 0.010 None 1.000 1 0 2005 2005
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box transcription factor 2 Transcription factor 503 0.405 0.808 0.71 0.010 None 1.000 1 0 2006 2006
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.010 None 1.000 1 1 2019 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.020 None 1.000 2 0 2016 2019
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.110 None 1.000 1 0 2015 2015
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.010 None 1.000 1 0 1999 1999
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.010 None < 0.001 1 0 2019 2019