Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.110 None 1.000 1 0 2015 2015
Entrez Id: 1999
Gene Symbol: ELF3
ELF3
P78545 E74 like ETS transcription factor 3 Transcription factor 112 0.551 0.808 0.98 0.030 None 1.000 3 0 2016 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.020 None 1.000 2 0 2018 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.020 None 1.000 2 0 2015 2015
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.020 None 1.000 2 0 2017 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.020 None 1.000 2 0 2016 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.020 None 1.000 2 0 1994 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.020 None 1.000 2 0 2015 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.020 None 1.000 2 0 2018 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.020 None 1.000 2 0 2018 2018
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.020 None 1.000 2 0 2018 2018
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.020 None 1.000 2 0 2017 2017
Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC
P98088 mucin 5AC, oligomeric mucus/gel-forming Enzyme modulator 224 0.483 0.808 1.0E-08 0.020 None 1.000 2 0 2006 2019
Entrez Id: 5566
Gene Symbol: PRKACA
PRKACA
P17612 protein kinase cAMP-activated catalytic subunit alpha Kinase 88 0.606 0.692 0.97 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.010 None 1.000 1 0 2005 2005
Entrez Id: 57534
Gene Symbol: MIB1
MIB1
Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 329 0.438 0.769 3.4E-88 0.010 None 1.000 1 0 1999 1999
Entrez Id: 6041
Gene Symbol: RNASEL
RNASEL
Q05823 ribonuclease L Kinase 85 0.579 0.692 2.0E-10 0.010 None 1.000 1 0 2012 2012
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box transcription factor 2 Transcription factor 503 0.405 0.808 0.71 0.010 None 1.000 1 0 2006 2006
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.010 None 1.000 1 0 2004 2004
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.010 None 1.000 1 0 2013 2013
Entrez Id: 840
Gene Symbol: CASP7
CASP7
P55210 caspase 7 Enzyme 83 0.581 0.654 5.4E-05 0.010 None < 0.001 1 0 2013 2013
Entrez Id: 842
Gene Symbol: CASP9
CASP9
P55211 caspase 9 Enzyme 293 0.458 0.808 7.4E-06 0.010 None < 0.001 1 0 2013 2013
Entrez Id: 55272
Gene Symbol: IMP3
IMP3
Q9NV31 IMP U3 small nucleolar ribonucleoprotein 3 Nucleic acid binding 97 0.566 0.462 1.5E-07 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5371
Gene Symbol: PML
PML
P29590 promyelocytic leukemia 274 0.477 0.846 0.21 0.010 None 1.000 1 0 2009 2009
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase Enzyme 439 0.425 0.923 2.3E-06 0.010 None 1.000 1 0 2005 2005