Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.200 None 1.000 1 0 2014 2014
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.300 strong 1.000 1 0 1996 1996
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.010 None 1.000 1 0 2013 2013
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.010 None 1.000 1 0 2005 2005
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.200 None 1.000 1 0 2004 2004
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.020 None 1.000 2 0 2005 2006
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14 		Q16539 mitogen-activated protein kinase 14 Kinase 626 0.379 0.923 0.37 0.010 None 1.000 1 0 2013 2013
Entrez Id: 7965
Gene Symbol: AIMP2
AIMP2 		Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 555 0.393 0.923 8.0E-03 0.010 None 1.000 1 0 2013 2013
Entrez Id: 1398
Gene Symbol: CRK
CRK 		P46108 CRK proto-oncogene, adaptor protein 544 0.394 0.923 0.96 0.010 None 1.000 1 0 2013 2013
Entrez Id: 9402
Gene Symbol: GRAP2
GRAP2 		O75791 GRB2 related adaptor protein 2 538 0.394 0.923 1.5E-04 0.010 None 1.000 1 0 2013 2013
Entrez Id: 26073
Gene Symbol: POLDIP2
POLDIP2 		Q9Y2S7 DNA polymerase delta interacting protein 2 530 0.396 0.923 0.41 0.010 None 1.000 1 0 2013 2013
Entrez Id: 10598
Gene Symbol: AHSA1
AHSA1 		O95433 activator of HSP90 ATPase activity 1 526 0.396 0.923 1.00 0.010 None 1.000 1 0 2013 2013
Entrez Id: 25897
Gene Symbol: RNF19A
RNF19A 		Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 523 0.397 0.923 2.5E-02 0.010 None 1.000 1 0 2013 2013
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1 		P26358 DNA methyltransferase 1 Epigenetic regulator 496 0.406 0.885 1.00 0.010 None 1.000 1 0 2010 2010
Entrez Id: 5894
Gene Symbol: RAF1
RAF1 		P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 470 0.418 0.885 0.85 0.200 None 1.000 2 0 2011 2012
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A 		Q9Y6K1 DNA methyltransferase 3 alpha 350 0.445 0.846 7.4E-39 0.300 strong 1.000 1 0 2018 2018
Entrez Id: 545
Gene Symbol: ATR
ATR 		Q13535 ATR serine/threonine kinase Kinase 321 0.456 0.923 3.5E-09 0.800 strong 1.000 15 2 2003 2018
Entrez Id: 3981
Gene Symbol: LIG4
LIG4 		P49917 DNA ligase 4 293 0.478 0.846 4.2E-06 0.320 strong 1.000 3 0 2001 2015
Entrez Id: 6654
Gene Symbol: SOS1
SOS1 		Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 261 0.485 0.808 1.00 0.200 None 1.000 1 0 2010 2010
Entrez Id: 2176
Gene Symbol: FANCC
FANCC 		Q00597 FA complementation group C 218 0.507 0.808 2.8E-13 0.010 None 1.000 1 0 1999 1999
Entrez Id: 3014
Gene Symbol: H2AX
H2AX 		P16104 H2A.X variant histone Nucleic acid binding 212 0.484 0.808 0.18 0.010 None 1.000 1 0 2011 2011
Entrez Id: 2175
Gene Symbol: FANCA
FANCA 		O15360 FA complementation group A 211 0.505 0.731 1.6E-68 0.010 None 1.000 1 0 1999 1999
Entrez Id: 969
Gene Symbol: CD69
CD69 		Q07108 CD69 molecule 206 0.488 0.923 3.0E-02 0.010 None 1.000 1 0 2010 2010
Entrez Id: 1111
Gene Symbol: CHEK1
CHEK1 		O14757 checkpoint kinase 1 Kinase 195 0.492 0.808 3.1E-08 0.010 None 1.000 1 0 2005 2005
Entrez Id: 7518
Gene Symbol: XRCC4
XRCC4 		Q13426 X-ray repair cross complementing 4 192 0.528 0.769 8.3E-07 0.300 strong 1.000 1 0 2014 2014