Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.040 None 1.000 4 0 2006 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.100 None 0.917 12 0 1996 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.030 None 1.000 3 0 2006 2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1604 0.276 0.962 0.13 0.100 None 0.917 12 0 2000 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1533 0.281 0.923 5.9E-03 0.030 None 1.000 3 1 2008 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1334 0.287 0.962 3.7E-02 0.020 None 1.000 2 0 2009 2017
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 1361 0.288 0.962 0.47 0.060 None 0.833 6 0 2010 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1294 0.291 0.885 0.56 0.010 None 1.000 1 0 2016 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.010 None 1.000 1 0 2008 2008
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1410 0.299 0.962 3.7E-03 0.010 None 1.000 1 0 2020 2020
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1173 0.310 0.962 2.7E-04 0.100 None 1.000 11 0 2000 2020
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		P05019 insulin like growth factor 1 1050 0.318 0.885 0.27 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		P13500 C-C motif chemokine ligand 2 Signaling 994 0.321 0.962 0.61 0.010 None 1.000 1 0 2013 2013
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		Q16552 interleukin 17A 1034 0.324 0.923 4.3E-02 0.040 None 1.000 4 0 2007 2019
Entrez Id: 60
Gene Symbol: ACTB
ACTB 		P60709 actin beta Cellular structure 957 0.325 0.923 0.99 0.010 None 1.000 1 0 2020 2020
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 935 0.330 0.923 1.00 0.020 None 1.000 2 0 2000 2019
Entrez Id: 3565
Gene Symbol: IL4
IL4 		P05112 interleukin 4 926 0.332 0.962 4.7E-03 0.030 None 1.000 3 0 2010 2017
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		P01583 interleukin 1 alpha 932 0.333 0.962 1.6E-04 0.030 None 1.000 3 0 2000 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 826 0.333 0.923 0.84 0.010 None 1.000 1 0 2012 2012
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 765 0.343 0.885 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		P42574 caspase 3 Enzyme 722 0.351 0.923 0.10 0.010 None 1.000 1 0 2019 2019
Entrez Id: 7421
Gene Symbol: VDR
VDR 		P11473 vitamin D receptor Nuclear receptor 757 0.352 0.885 1.7E-05 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 739 0.357 0.885 3.6E-03 0.020 None 1.000 2 0 2018 2019
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		O60603 toll like receptor 2 704 0.361 0.923 1.0E-06 0.060 None 1.000 6 0 2012 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 702 0.361 0.962 8.1E-04 0.020 None 1.000 2 0 2013 2019