Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.090 None 1.000 9 0 2000 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.080 None 1.000 8 0 1998 2015
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.070 None 1.000 7 2 2010 2019
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.030 None 1.000 3 0 2005 2013
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.030 None 1.000 3 0 2017 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.020 None 1.000 2 1 1999 2008
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
Q12882 dihydropyrimidine dehydrogenase Enzyme 249 0.493 0.846 3.4E-22 0.020 None 1.000 2 0 2005 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.020 None 0.500 2 0 2011 2013
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
P48061 C-X-C motif chemokine ligand 12 626 0.379 0.846 0.12 0.010 None 1.000 1 0 2016 2016
Entrez Id: 581
Gene Symbol: BAX
BAX
Q07812 BCL2 associated X, apoptosis regulator Signaling 420 0.417 0.885 0.32 0.010 None 1.000 1 0 2007 2007
Entrez Id: 57214
Gene Symbol: CEMIP
CEMIP
Q8WUJ3 cell migration inducing hyaluronidase 1 64 0.617 0.615 4.4E-17 0.010 None 1.000 1 0 2015 2015
Entrez Id: 56994
Gene Symbol: CHPT1
CHPT1
Q8WUD6 choline phosphotransferase 1 Enzyme 253 0.474 0.846 2.4E-04 0.010 None 1.000 1 0 2007 2007
Entrez Id: 5670
Gene Symbol: PSG2
PSG2
P11465 pregnancy specific beta-1-glycoprotein 2 210 0.492 0.731 1.4E-30 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box transcription factor 2 Transcription factor 503 0.405 0.808 0.71 0.010 None 1.000 1 0 2017 2017
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.010 None 1.000 1 0 2001 2001
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.010 None 1.000 1 0 2008 2008
Entrez Id: 7424
Gene Symbol: VEGFC
VEGFC
P49767 vascular endothelial growth factor C Signaling 291 0.459 0.769 0.50 0.010 None 1.000 1 0 2008 2008
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 739 0.362 0.923 1.8E-02 0.010 None 1.000 1 0 2016 2016
Entrez Id: 79947
Gene Symbol: DHDDS
DHDDS
Q86SQ9 dehydrodolichyl diphosphate synthase subunit Enzyme 308 0.468 0.885 0.25 0.010 None 1.000 1 0 2007 2007
Entrez Id: 80316
Gene Symbol: PPP1R2C
PPP1R2C
O14990 PPP1R2C family member C Enzyme modulator 231 0.478 0.846 0.010 None 1.000 1 0 2019 2019
Entrez Id: 831
Gene Symbol: CAST
CAST
P20810 calpastatin 141 0.541 0.846 4.1E-12 0.010 None 1.000 1 0 2013 2013
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
O43490 prominin 1 Transporter 477 0.410 0.846 1.9E-22 0.010 None 1.000 1 0 2017 2017
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.010 None 1.000 1 0 2017 2017
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
Q9BZS1 forkhead box P3 688 0.368 0.846 0.99 0.010 None 1.000 1 0 2017 2017