Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.420 None 1.000 2 0 2001 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.200 None 0.979 47 3 1993 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 942 0.328 0.923 6.0E-03 0.200 None 1.000 14 0 1990 2018
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3 		P22607 fibroblast growth factor receptor 3 Kinase 377 0.391 0.846 1.6E-05 0.170 None 0.875 7 0 2009 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 888 0.319 0.846 1.00 0.140 None 0.800 4 2 2009 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.120 None 0.667 2 0 2012 2016
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.120 None 0.667 2 0 2000 2016
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 765 0.343 0.885 1.00 0.110 None 1.000 1 0 2012 2014
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		P11362 fibroblast growth factor receptor 1 Kinase 470 0.362 0.885 1.00 0.110 None 1.000 1 0 2016 2017
Entrez Id: 5925
Gene Symbol: RB1
RB1 		P06400 RB transcriptional corepressor 1 Nucleic acid binding 220 0.444 0.885 1.00 0.110 None 1.000 1 0 1998 1998
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 457 0.378 0.885 8.0E-02 0.110 None 1.000 1 0 1998 2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.110 None 1.000 1 0 2000 2000
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.110 None 1.000 1 0 2012 2016
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1011 0.311 0.962 0.98 0.110 None 1.000 1 0 2012 2012
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 935 0.330 0.923 1.00 0.110 None 1.000 1 0 2016 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.080 None 1.000 8 0 2002 2018
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1294 0.291 0.885 0.56 0.070 None 1.000 7 2 1996 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.050 None 1.000 5 0 2000 2019
Entrez Id: 54474
Gene Symbol: KRT20
KRT20 		P35900 keratin 20 545 0.388 0.846 9.1E-11 0.050 None 1.000 5 0 1998 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.050 None 1.000 5 0 1991 2018
Entrez Id: 4830
Gene Symbol: NME1
NME1 		P15531 NME/NM23 nucleoside diphosphate kinase 1 Kinase 317 0.443 0.808 3.2E-03 0.040 None 1.000 4 0 1996 2000
Entrez Id: 4513
Gene Symbol: COX2
COX2 		P00403 cytochrome c oxidase subunit II Enzyme 762 0.352 0.962 0.040 None 1.000 4 0 2000 2019
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12 		MT-CO2 pseudogene 12 703 0.368 0.962 0.040 None 1.000 4 0 2000 2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2 		Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 535 0.376 0.885 1.00 0.040 None 1.000 4 0 2005 2019
Entrez Id: 220296
Gene Symbol: HEPACAM
HEPACAM 		Q14CZ8 hepatic and glial cell adhesion molecule 45 0.621 0.500 0.87 0.040 None 0.750 4 0 2010 2015