Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 201163
Gene Symbol: FLCN
FLCN 		Q8NFG4 folliculin 75 0.537 0.885 0.79 0.900 None 0.938 14 5 2002 2020
Entrez Id: 7428
Gene Symbol: VHL
VHL 		P40337 von Hippel-Lindau tumor suppressor Enzyme 239 0.443 0.846 8.0E-02 0.800 None 0.972 282 11 1989 2019
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A 		P20823 HNF1 homeobox A Nucleic acid binding 205 0.478 0.846 0.96 0.720 strong 1.000 2 0 1994 1999
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1 		Q86U86 polybromo 1 Epigenetic regulator 81 0.566 0.615 1.00 0.700 None 1.000 54 0 2011 2020
Entrez Id: 29072
Gene Symbol: SETD2
SETD2 		Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 353 0.424 0.846 1.00 0.700 None 0.957 41 0 2003 2019
Entrez Id: 4968
Gene Symbol: OGG1
OGG1 		O15527 8-oxoguanine DNA glycosylase 266 0.453 0.808 3.9E-12 0.640 None 1.000 4 1 2003 2011
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 765 0.343 0.885 1.00 0.600 None 0.984 63 0 2005 2020
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		Q92560 BRCA1 associated protein 1 Enzyme 203 0.454 0.731 0.99 0.600 None 0.982 53 0 2011 2019
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 501 0.380 0.846 0.97 0.600 None 0.969 31 2 1999 2020
Entrez Id: 7248
Gene Symbol: TSC1
TSC1 		Q92574 TSC complex subunit 1 248 0.440 0.808 1.00 0.600 None 1.000 13 0 1995 2020
Entrez Id: 8242
Gene Symbol: KDM5C
KDM5C 		P41229 lysine demethylase 5C 42 0.581 0.538 1.00 0.600 None 1.000 10 0 2011 2017
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B 		P35680 HNF1 homeobox B Nucleic acid binding 192 0.473 0.808 1.00 0.550 None 0.833 5 0 1999 2017
Entrez Id: 7030
Gene Symbol: TFE3
TFE3 		P19532 transcription factor binding to IGHM enhancer 3 116 0.542 0.654 0.98 0.400 None 0.988 82 0 2001 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.400 None 0.951 78 5 1991 2019
Entrez Id: 2034
Gene Symbol: EPAS1
EPAS1 		Q99814 endothelial PAS domain protein 1 Transcription factor 260 0.454 0.731 0.60 0.400 None 0.930 57 5 2001 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.400 None 1.000 49 0 2006 2019
Entrez Id: 3791
Gene Symbol: KDR
KDR 		P35968 kinase insert domain receptor Kinase 561 0.378 0.885 1.00 0.400 None 0.972 36 0 2001 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.400 None 1.000 36 0 1998 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.400 None 0.964 27 0 1993 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		P09488 glutathione S-transferase mu 1 581 0.380 0.923 2.1E-03 0.400 None 0.929 14 0 2000 2018
Entrez Id: 238
Gene Symbol: ALK
ALK 		Q9UM73 ALK receptor tyrosine kinase Kinase 484 0.396 0.846 3.2E-06 0.400 None 0.929 13 0 2012 2019
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		P49815 TSC complex subunit 2 Enzyme modulator 276 0.439 0.808 1.00 0.400 None 1.000 13 0 2001 2020
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1 		P30711 glutathione S-transferase theta 1 497 0.393 0.923 1.5E-04 0.400 None 1.000 12 0 1999 2018
Entrez Id: 4286
Gene Symbol: MITF
MITF 		O75030 melanocyte inducing transcription factor 130 0.499 0.808 0.98 0.400 None 1.000 12 2 2009 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 942 0.328 0.923 6.0E-03 0.400 None 0.900 10 0 1990 2011