Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 1.000 12 0 1995 2014
Entrez Id: 8626
Gene Symbol: TP63
TP63
Q9H3D4 tumor protein p63 Transcription factor 816 0.362 0.769 1.00 0.060 None 1.000 6 0 1999 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.060 None 1.000 6 0 2003 2019
Entrez Id: 9968
Gene Symbol: MED12
MED12
Q93074 mediator complex subunit 12 Transcription factor 340 0.476 0.769 1.00 0.050 None 1.000 5 0 2013 2017
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.040 None 1.000 4 0 2007 2019
Entrez Id: 3815
Gene Symbol: KIT
KIT
P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.040 None 1.000 4 0 2009 2019
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.030 None 1.000 3 0 2003 2017
Entrez Id: 1462
Gene Symbol: VCAN
VCAN
P13611 versican Extracellular structure 205 0.497 0.808 1.00 0.030 None 1.000 3 0 2004 2016
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.030 None 1.000 3 0 2011 2015
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.030 None 1.000 3 0 2007 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.030 None 1.000 3 0 2007 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.030 None 1.000 3 0 2007 2019
Entrez Id: 7431
Gene Symbol: VIM
VIM
P08670 vimentin 644 0.372 0.846 0.71 0.020 None 1.000 2 0 2010 2012
Entrez Id: 800
Gene Symbol: CALD1
CALD1
Q05682 caldesmon 1 94 0.578 0.692 1.00 0.020 None 1.000 2 0 2017 2018
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
P01344 insulin like growth factor 2 604 0.390 0.885 4.4E-02 0.020 None 1.000 2 0 1988 1990
Entrez Id: 406985
Gene Symbol: MIR200C
MIR200C
microRNA 200c 202 0.486 0.846 0.020 None 1.000 2 0 2012 2015
Entrez Id: 22800
Gene Symbol: RRAS2
RRAS2
P62070 RAS related 2 Enzyme modulator 48 0.656 0.500 0.97 0.020 None 1.000 2 0 1995 1998
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.020 None 1.000 2 0 2019 2019
Entrez Id: 6591
Gene Symbol: SNAI2
SNAI2
O43623 snail family transcriptional repressor 2 189 0.505 0.692 0.80 0.020 None 1.000 2 0 2005 2010
Entrez Id: 3342
Gene Symbol: HTC2
HTC2
hypertrichosis 2 (generalized, congenital) 511 0.392 0.808 0.020 None 1.000 2 0 2014 2015
Entrez Id: 8091
Gene Symbol: HMGA2
HMGA2
P52926 high mobility group AT-hook 2 Nucleic acid binding 382 0.429 0.808 0.87 0.020 None 1.000 2 0 2002 2014
Entrez Id: 9734
Gene Symbol: HDAC9
HDAC9
Q9UKV0 histone deacetylase 9 Epigenetic regulator 340 0.439 0.846 1.00 0.020 None 1.000 2 0 2019 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.020 None 1.000 2 0 1999 2018
Entrez Id: 55733
Gene Symbol: HHAT
HHAT
Q5VTY9 hedgehog acyltransferase Enzyme 75 0.608 0.577 3.2E-08 0.020 None 1.000 2 0 1999 2012
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.020 None 1.000 2 0 2010 2012