Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5052
Gene Symbol: PRDX1
PRDX1
Q06830 peroxiredoxin 1 Enzyme 237 0.485 0.846 7.7E-10 0.010 None 1.000 1 0 2013 2013
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 321 0.459 0.808 8.9E-10 0.010 None 1.000 1 1 2010 2010
Entrez Id: 5730
Gene Symbol: PTGDS
PTGDS
P41222 prostaglandin D2 synthase Enzyme 195 0.503 0.846 5.1E-03 0.010 None 1.000 1 0 2008 2008
Entrez Id: 3485
Gene Symbol: IGFBP2
IGFBP2
P18065 insulin like growth factor binding protein 2 Enzyme modulator 241 0.478 0.769 0.12 0.010 None 1.000 1 0 2010 2010
Entrez Id: 3488
Gene Symbol: IGFBP5
IGFBP5
P24593 insulin like growth factor binding protein 5 Enzyme modulator 126 0.544 0.692 0.96 0.010 None 1.000 1 0 2010 2010
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.010 None 1.000 1 0 1999 1999
Entrez Id: 894
Gene Symbol: CCND2
CCND2
P30279 cyclin D2 Enzyme modulator 241 0.477 0.808 0.99 0.010 None < 0.001 1 0 1999 1999
Entrez Id: 972
Gene Symbol: CD74
CD74
P04233 CD74 molecule Enzyme modulator 170 0.512 0.808 0.25 0.010 None 1.000 1 0 2010 2010
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 447 0.424 0.846 1.00 0.010 None 1.000 1 0 2012 2012
Entrez Id: 27239
Gene Symbol: GPR162
GPR162
Q16538 G protein-coupled receptor 162 G-protein coupled receptor 51 0.631 0.654 9.4E-03 0.010 None 1.000 1 0 2015 2015
Entrez Id: 2890
Gene Symbol: GRIA1
GRIA1
P42261 glutamate ionotropic receptor AMPA type subunit 1 Ion channel 126 0.570 0.577 1.00 0.010 None 1.000 1 0 2008 2008
Entrez Id: 361
Gene Symbol: AQP4
AQP4
P55087 aquaporin 4 Ion channel 311 0.456 0.885 2.3E-03 0.010 None 1.000 1 0 2017 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.070 None 1.000 7 0 2001 2015
Entrez Id: 1021
Gene Symbol: CDK6
CDK6
Q00534 cyclin dependent kinase 6 Kinase 266 0.471 0.731 0.98 0.010 None 1.000 1 0 2013 2013
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.010 None 1.000 1 0 2006 2006
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 731 0.380 0.808 1.00 0.010 None 1.000 1 0 2001 2001
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7
O14733 mitogen-activated protein kinase kinase 7 Kinase 408 0.419 0.808 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 470 0.418 0.885 0.85 0.010 None 1.000 1 0 2013 2013
Entrez Id: 6098
Gene Symbol: ROS1
ROS1
P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 356 0.439 0.885 1.6E-72 0.010 None 1.000 1 0 2013 2013
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 54840
Gene Symbol: APTX
APTX
Q7Z2E3 aprataxin Nucleic acid binding 94 0.590 0.500 4.0E-10 0.020 None 1.000 2 0 2009 2013
Entrez Id: 8091
Gene Symbol: HMGA2
HMGA2
P52926 high mobility group AT-hook 2 Nucleic acid binding 382 0.429 0.808 0.87 0.020 None 1.000 2 0 2014 2015
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.010 None 1.000 1 0 1997 1997
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 Nucleic acid binding 339 0.444 0.885 1.00 0.010 None 1.000 1 0 2001 2001
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.010 None 1.000 1 0 2006 2006