Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.100 None 1.000 21 0 2009 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.100 None 1.000 21 1 1994 2019
Entrez Id: 100124700
Gene Symbol: HOTAIR
HOTAIR
HOX transcript antisense RNA 234 0.475 0.769 0.100 None 0.950 20 4 2014 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.100 None 1.000 20 0 2000 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.100 None 0.947 19 3 2009 2019
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.100 None 0.947 19 4 2005 2019
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 379 0.436 0.846 1.1E-17 0.100 None 0.889 18 2 2006 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.100 None 1.000 18 0 2007 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.100 None 1.000 17 1 1999 2019
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 541 0.393 0.923 1.5E-04 0.100 None 0.800 15 0 2000 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.100 None 0.800 15 2 2000 2019
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
microRNA 34a 428 0.421 0.846 0.100 None 1.000 14 0 2010 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.100 None 0.923 13 0 2004 2019
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1
P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 504 0.407 0.885 8.9E-03 0.100 None 1.000 13 0 1994 2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 336 0.435 0.846 0.100 None 1.000 13 0 2010 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.100 None 1.000 13 1 2002 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.100 None 1.000 13 1 2005 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 1.000 12 3 1995 2019
Entrez Id: 2305
Gene Symbol: FOXM1
FOXM1
Q08050 forkhead box M1 323 0.441 0.769 7.4E-04 0.100 None 1.000 11 0 2008 2020
Entrez Id: 23705
Gene Symbol: CADM1
CADM1
Q9BY67 cell adhesion molecule 1 205 0.491 0.769 0.66 0.100 None 0.909 11 0 2004 2019
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.100 None 0.727 11 2 2005 2019
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
Q9NR96 toll like receptor 9 457 0.411 0.885 9.8E-06 0.100 None 0.818 11 2 2011 2020
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.100 None 1.000 11 1 2012 2019
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.100 None 1.000 11 1 1998 2017
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.100 None 1.000 11 5 2009 2019