Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.010 None 1.000 1 0 2001 2001
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
P11166 solute carrier family 2 member 1 Transporter 687 0.388 0.808 0.99 0.010 None 1.000 1 0 2012 2012
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.080 None 1.000 8 1 1998 2019
Entrez Id: 23462
Gene Symbol: HEY1
HEY1
Q9Y5J3 hes related family bHLH transcription factor with YRPW motif 1 Transcription factor 110 0.551 0.692 5.0E-02 0.300 None 1.000 1 0 2010 2010
Entrez Id: 3280
Gene Symbol: HES1
HES1
Q14469 hes family bHLH transcription factor 1 Transcription factor 243 0.468 0.885 0.71 0.300 None 1.000 1 0 2010 2010
Entrez Id: 64321
Gene Symbol: SOX17
SOX17
Q9H6I2 SRY-box transcription factor 17 Transcription factor 113 0.555 0.615 0.88 0.010 None 1.000 1 0 2014 2014
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box transcription factor 2 Transcription factor 503 0.405 0.808 0.71 0.010 None 1.000 1 0 2011 2011
Entrez Id: 6938
Gene Symbol: TCF12
TCF12
Q99081 transcription factor 12 Transcription factor 102 0.565 0.654 0.68 0.010 None 1.000 1 0 2015 2015
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.020 None 1.000 2 0 1999 2011
Entrez Id: 6750
Gene Symbol: SST
SST
P61278 somatostatin Signaling 535 0.399 0.885 0.34 0.020 None 1.000 2 0 2015 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.020 None 1.000 2 0 1998 2014
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor Signaling 409 0.434 0.885 0.20 0.300 None 1.000 1 0 2009 2009
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
O15123 angiopoietin 2 Signaling 457 0.410 0.846 0.83 0.010 None 1.000 1 0 2014 2014
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
P17931 galectin 3 Signaling 557 0.392 0.846 2.3E-05 0.010 None 1.000 1 0 2004 2004
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
P01127 platelet derived growth factor subunit B Signaling 301 0.488 0.846 0.77 0.010 None 1.000 1 0 2011 2011
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.020 None 1.000 2 0 2007 2014
Entrez Id: 54840
Gene Symbol: APTX
APTX
Q7Z2E3 aprataxin Nucleic acid binding 94 0.590 0.500 4.0E-10 0.020 None 1.000 2 0 2013 2013
Entrez Id: 25913
Gene Symbol: POT1
POT1
Q9NUX5 protection of telomeres 1 Nucleic acid binding 107 0.560 0.731 0.85 0.300 None 1.000 1 0 2015 2015
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.010 None 1.000 1 0 2001 2001
Entrez Id: 4194
Gene Symbol: MDM4
MDM4
O15151 MDM4 regulator of p53 Nucleic acid binding 265 0.461 0.808 1.00 0.010 None 1.000 1 0 1999 1999
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.010 None 1.000 1 0 2013 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.060 None 1.000 6 0 1996 2011
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
P16234 platelet derived growth factor receptor alpha Kinase 452 0.415 0.808 1.00 0.030 None 1.000 3 0 2000 2014
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.020 None 1.000 2 0 2001 2008
Entrez Id: 3815
Gene Symbol: KIT
KIT
P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.020 None 1.000 2 0 2007 2014