Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1806
Gene Symbol: DPYD
DPYD 		Q12882 dihydropyrimidine dehydrogenase Enzyme 249 0.493 0.846 3.4E-22 0.010 None 1.000 1 0 2010 2010
Entrez Id: 1840
Gene Symbol: DTX1
DTX1 		Q86Y01 deltex E3 ubiquitin ligase 1 Enzyme 38 0.656 0.500 9.9E-04 0.300 None 1.000 1 0 2010 2010
Entrez Id: 2194
Gene Symbol: FASN
FASN 		P49327 fatty acid synthase Enzyme 245 0.474 0.846 1.00 0.010 None 1.000 1 0 2013 2013
Entrez Id: 4175
Gene Symbol: MCM6
MCM6 		Q14566 minichromosome maintenance complex component 6 Enzyme 41 0.666 0.615 0.98 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5321
Gene Symbol: PLA2G4A
PLA2G4A 		P47712 phospholipase A2 group IVA Enzyme 202 0.496 0.846 6.0E-05 0.010 None 1.000 1 0 2006 2006
Entrez Id: 56994
Gene Symbol: CHPT1
CHPT1 		Q8WUD6 choline phosphotransferase 1 Enzyme 253 0.474 0.846 2.4E-04 0.010 None < 0.001 1 0 2008 2008
Entrez Id: 79947
Gene Symbol: DHDDS
DHDDS 		Q86SQ9 dehydrodolichyl diphosphate synthase subunit Enzyme 308 0.468 0.885 0.25 0.010 None < 0.001 1 0 2008 2008
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.010 None 1.000 1 0 2011 2011
Entrez Id: 8605
Gene Symbol: PLA2G4C
PLA2G4C 		Q9UP65 phospholipase A2 group IVC Enzyme 24 0.705 0.385 1.7E-13 0.010 None 1.000 1 0 2006 2006
Entrez Id: 10309
Gene Symbol: CCNO
CCNO 		P22674 cyclin O Enzyme modulator 67 0.621 0.538 3.5E-03 0.030 None 1.000 3 0 2013 2016
Entrez Id: 3485
Gene Symbol: IGFBP2
IGFBP2 		P18065 insulin like growth factor binding protein 2 Enzyme modulator 241 0.478 0.769 0.12 0.010 None 1.000 1 0 2009 2009
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.010 None 1.000 1 0 2018 2018
Entrez Id: 11010
Gene Symbol: GLIPR1
GLIPR1 		P48060 GLI pathogenesis related 1 Immune response 48 0.636 0.500 2.1E-14 0.010 None 1.000 1 0 2007 2007
Entrez Id: 9780
Gene Symbol: PIEZO1
PIEZO1 		Q92508 piezo type mechanosensitive ion channel component 1 Ion channel 130 0.552 0.769 3.9E-21 0.010 None 1.000 1 0 1999 1999
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.060 None 1.000 6 0 1996 2011
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		P16234 platelet derived growth factor receptor alpha Kinase 452 0.415 0.808 1.00 0.030 None 1.000 3 0 2000 2014
Entrez Id: 1019
Gene Symbol: CDK4
CDK4 		P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.020 None 1.000 2 0 2001 2008
Entrez Id: 3815
Gene Symbol: KIT
KIT 		P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.020 None 1.000 2 0 2007 2014
Entrez Id: 1017
Gene Symbol: CDK2
CDK2 		P24941 cyclin dependent kinase 2 Kinase 270 0.456 0.692 0.61 0.010 None 1.000 1 0 1999 1999
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.010 None 1.000 1 1 2004 2004
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.020 None 1.000 2 0 2007 2014
Entrez Id: 54840
Gene Symbol: APTX
APTX 		Q7Z2E3 aprataxin Nucleic acid binding 94 0.590 0.500 4.0E-10 0.020 None 1.000 2 0 2013 2013
Entrez Id: 25913
Gene Symbol: POT1
POT1 		Q9NUX5 protection of telomeres 1 Nucleic acid binding 107 0.560 0.731 0.85 0.300 None 1.000 1 0 2015 2015
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.010 None 1.000 1 0 2001 2001
Entrez Id: 4194
Gene Symbol: MDM4
MDM4 		O15151 MDM4 regulator of p53 Nucleic acid binding 265 0.461 0.808 1.00 0.010 None 1.000 1 0 1999 1999