Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.080 None 0.875 8 0 2012 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.070 None 1.000 7 2 2013 2019
Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC
P98088 mucin 5AC, oligomeric mucus/gel-forming Enzyme modulator 224 0.483 0.808 1.0E-08 0.070 None 0.857 7 0 2003 2019
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
Q86U86 polybromo 1 Epigenetic regulator 105 0.566 0.615 1.00 0.370 None 1.000 7 0 2013 2019
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
O14497 AT-rich interaction domain 1A 341 0.455 0.846 1.00 0.370 None 1.000 7 0 2013 2019
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.060 None 1.000 6 0 2016 2019
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
P15941 mucin 1, cell surface associated 594 0.384 0.885 1.9E-02 0.050 None 1.000 5 0 2001 2019
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.050 None 0.800 5 0 2010 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.050 None 0.800 5 0 2001 2019
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.050 None 0.800 5 0 1999 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.040 None 1.000 4 0 2013 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.040 None 1.000 4 0 2017 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.040 None 1.000 4 0 2006 2019
Entrez Id: 7431
Gene Symbol: VIM
VIM
P08670 vimentin 644 0.372 0.846 0.71 0.040 None 1.000 4 0 2013 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.030 None 1.000 3 0 2017 2019
Entrez Id: 6662
Gene Symbol: SOX9
SOX9
P48436 SRY-box transcription factor 9 466 0.419 0.846 1.00 0.030 None 1.000 3 0 2018 2019
Entrez Id: 1087
Gene Symbol: CEACAM7
CEACAM7
Q14002 CEA cell adhesion molecule 7 202 0.494 0.769 1.3E-07 0.030 None 1.000 3 0 2016 2019
Entrez Id: 6282
Gene Symbol: S100A11
S100A11
P31949 S100 calcium binding protein A11 Calcium-binding protein 103 0.556 0.731 8.5E-03 0.030 None 1.000 3 0 2015 2019
Entrez Id: 5774
Gene Symbol: PTPN3
PTPN3
P26045 protein tyrosine phosphatase non-receptor type 3 51 0.647 0.462 6.7E-09 0.030 None 1.000 3 0 2014 2019
Entrez Id: 5670
Gene Symbol: PSG2
PSG2
P11465 pregnancy specific beta-1-glycoprotein 2 210 0.492 0.731 1.4E-30 0.030 None 1.000 3 0 2016 2019
Entrez Id: 1084
Gene Symbol: CEACAM3
CEACAM3
P40198 CEA cell adhesion molecule 3 204 0.494 0.731 1.1E-09 0.030 None 1.000 3 0 2016 2019
Entrez Id: 339896
Gene Symbol: GADL1
GADL1
Q6ZQY3 glutamate decarboxylase like 1 192 0.497 0.808 1.4E-21 0.020 None 1.000 2 0 2018 2019
Entrez Id: 4087
Gene Symbol: SMAD2
SMAD2
Q15796 SMAD family member 2 Transcription factor 289 0.456 0.808 1.00 0.020 None 1.000 2 0 2018 2019
Entrez Id: 5567
Gene Symbol: PRKACB
PRKACB
P22694 protein kinase cAMP-activated catalytic subunit beta Kinase 33 0.670 0.577 0.35 0.310 None 1.000 2 0 2015 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.020 None 1.000 2 0 2012 2019