Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.060 None 0.833 6 0 1994 2016
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.020 None 1.000 2 0 2014 2015
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 55272
Gene Symbol: IMP3
IMP3
Q9NV31 IMP U3 small nucleolar ribonucleoprotein 3 Nucleic acid binding 97 0.566 0.462 1.5E-07 0.010 None 1.000 1 0 2016 2016
Entrez Id: 57534
Gene Symbol: MIB1
MIB1
Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 329 0.438 0.769 3.4E-88 0.010 None 1.000 1 0 1995 1995
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.010 None 1.000 1 0 2016 2016
Entrez Id: 6590
Gene Symbol: SLPI
SLPI
P03973 secretory leukocyte peptidase inhibitor Enzyme modulator 310 0.449 0.846 9.0E-04 0.010 None 1.000 1 0 2014 2014
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.010 None 1.000 1 0 2016 2016
Entrez Id: 7095
Gene Symbol: SEC62
SEC62
Q99442 SEC62 homolog, preprotein translocation factor 43 0.653 0.308 0.98 0.010 None 1.000 1 0 2019 2019
Entrez Id: 7299
Gene Symbol: TYR
TYR
P14679 tyrosinase Enzyme 281 0.473 0.808 5.0E-32 0.010 None < 0.001 1 0 2017 2017
Entrez Id: 7430
Gene Symbol: EZR
EZR
P15311 ezrin Cellular structure 255 0.476 0.808 0.18 0.010 None 1.000 1 0 2017 2017
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
P37023 activin A receptor like type 1 Kinase 224 0.493 0.769 9.7E-04 0.010 None 1.000 1 0 2014 2014
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8
P28908 TNF receptor superfamily member 8 301 0.444 0.808 0.86 0.010 None 1.000 1 0 2014 2014
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.010 None 1.000 1 0 2001 2001
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.010 None 1.000 1 0 2002 2002
Entrez Id: 110806263
Gene Symbol: LOC110806263
LOC110806263
TERT 5' regulatory region 245 0.464 0.731 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
P11362 fibroblast growth factor receptor 1 Kinase 816 0.362 0.885 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
P22607 fibroblast growth factor receptor 3 Kinase 654 0.391 0.846 1.6E-05 0.010 None 1.000 1 0 2016 2016
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 731 0.380 0.808 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 2303
Gene Symbol: FOXC2
FOXC2
Q99958 forkhead box C2 Transcription factor 168 0.515 0.731 0.13 0.010 None 1.000 1 0 2001 2001
Entrez Id: 2828
Gene Symbol: GPR4
GPR4
P46093 G protein-coupled receptor 4 G-protein coupled receptor 34 0.674 0.462 0.10 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.010 None < 0.001 1 0 2001 2001
Entrez Id: 4286
Gene Symbol: MITF
MITF
O75030 melanocyte inducing transcription factor 244 0.499 0.808 0.98 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4288
Gene Symbol: MKI67
MKI67
P46013 marker of proliferation Ki-67 351 0.431 0.808 1.3E-28 0.010 None 1.000 1 0 1995 1995