Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 56 0.379 0.846 2.4E-25 0.800 None 0.988 2 4 1996 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.800 None 0.978 0 0 1991 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.600 None 0.985 6 0 1985 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 115 0.300 0.885 0.39 0.600 None 0.979 2 0 1995 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 57 0.367 0.923 9.2E-29 0.600 None 1.000 1 0 1997 2020
Entrez Id: 6794
Gene Symbol: STK11
STK11 		Q15831 serine/threonine kinase 11 Kinase 39 0.435 0.808 0.99 0.600 None 1.000 1 0 1999 2019
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		Q13485 SMAD family member 4 Transcription factor 47 0.401 0.808 1.00 0.600 None 1.000 0 0 1996 2020
Entrez Id: 2033
Gene Symbol: EP300
EP300 		Q09472 E1A binding protein p300 40 0.459 0.846 1.00 0.510 None 1.000 0 0 2004 2004
Entrez Id: 28
Gene Symbol: ABO
ABO 		P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 16 0.427 0.885 0.500 None 0.960 2 1 2009 2018
Entrez Id: 2494
Gene Symbol: NR5A2
NR5A2 		O00482 nuclear receptor subfamily 5 group A member 2 Nuclear receptor 19 0.563 0.731 0.24 0.500 None 1.000 2 1 2010 2018
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		Q86YC2 partner and localizer of BRCA2 33 0.485 0.769 3.0E-19 0.500 None 0.903 1 2 2009 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.400 None 0.963 4 0 1999 2019
Entrez Id: 3651
Gene Symbol: PDX1
PDX1 		P52945 pancreatic and duodenal homeobox 1 13 0.530 0.654 1.8E-02 0.400 None 0.958 3 0 2004 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 138 0.320 0.923 1.00 0.400 None 1.000 2 0 2003 2020
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 72 0.374 0.885 5.6E-47 0.400 None 1.000 2 0 2004 2020
Entrez Id: 7015
Gene Symbol: TERT
TERT 		O14746 telomerase reverse transcriptase Enzyme 72 0.374 0.846 0.99 0.400 None 1.000 2 0 2002 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 89 0.327 0.923 0.98 0.400 None 0.986 1 0 2003 2019
Entrez Id: 6690
Gene Symbol: SPINK1
SPINK1 		P00995 serine peptidase inhibitor Kazal type 1 10 0.492 0.808 0.31 0.400 None 0.833 1 0 2003 2018
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 109 0.310 0.962 2.7E-04 0.400 None 0.950 1 0 1999 2019
Entrez Id: 3791
Gene Symbol: KDR
KDR 		P35968 kinase insert domain receptor Kinase 53 0.378 0.885 1.00 0.400 None 1.000 1 0 2002 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 182 0.305 0.923 0.26 0.400 None 0.955 1 0 2002 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 138 0.305 0.923 1.9E-17 0.400 None 0.952 1 0 1995 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 91 0.344 0.923 1.00 0.400 None 1.000 1 0 2002 2020
Entrez Id: 6750
Gene Symbol: SST
SST 		P61278 somatostatin Signaling 56 0.399 0.885 0.34 0.400 None 1.000 1 0 1986 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.400 None 0.900 1 0 1995 2020