Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.060 None 1.000 6 0 2004 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.040 None 0.750 4 0 2017 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.030 None 1.000 3 0 2011 2019
Entrez Id: 6678
Gene Symbol: SPARC
SPARC
P09486 secreted protein acidic and cysteine rich Signaling 344 0.445 0.846 0.89 0.020 None 0.500 2 0 2015 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.020 None 1.000 2 0 2009 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.020 None 1.000 2 0 1998 2019
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase Enzyme 439 0.425 0.923 2.3E-06 0.020 None 1.000 2 0 2004 2005
Entrez Id: 1969
Gene Symbol: EPHA2
EPHA2
P29317 EPH receptor A2 Kinase 187 0.501 0.731 1.1E-05 0.020 None 1.000 2 0 2006 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.020 None 1.000 2 0 2013 2018
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
P01009 serpin family A member 1 Enzyme modulator 482 0.410 0.923 6.8E-08 0.010 None 1.000 1 0 2008 2008
Entrez Id: 4673
Gene Symbol: NAP1L1
NAP1L1
P55209 nucleosome assembly protein 1 like 1 Enzyme modulator 53 0.647 0.692 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6416
Gene Symbol: MAP2K4
MAP2K4
P45985 mitogen-activated protein kinase kinase 4 Kinase 100 0.559 0.692 1.00 0.010 None 1.000 1 0 2004 2004
Entrez Id: 5888
Gene Symbol: RAD51
RAD51
Q06609 RAD51 recombinase 363 0.447 0.846 2.7E-02 0.010 None 1.000 1 0 2011 2011
Entrez Id: 55872
Gene Symbol: PBK
PBK
Q96KB5 PDZ binding kinase Kinase 121 0.541 0.769 1.2E-06 0.010 None 1.000 1 0 2018 2018
Entrez Id: 54474
Gene Symbol: KRT20
KRT20
P35900 keratin 20 559 0.388 0.846 9.1E-11 0.010 None 1.000 1 0 1999 1999
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5329
Gene Symbol: PLAUR
PLAUR
Q03405 plasminogen activator, urokinase receptor 147 0.536 0.731 5.3E-03 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5058
Gene Symbol: PAK1
PAK1
Q13153 p21 (RAC1) activated kinase 1 Kinase 221 0.494 0.808 1.3E-03 0.010 None 1.000 1 0 2014 2014
Entrez Id: 5074
Gene Symbol: PAWR
PAWR
Q96IZ0 pro-apoptotic WT1 regulator 133 0.542 0.846 9.0E-02 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5223
Gene Symbol: PGAM1
PGAM1
P18669 phosphoglycerate mutase 1 62 0.621 0.615 2.6E-07 0.010 None 1.000 1 0 2018 2018
Entrez Id: 9002
Gene Symbol: F2RL3
F2RL3
Q96RI0 F2R like thrombin or trypsin receptor 3 G-protein coupled receptor 133 0.539 0.769 4.1E-05 0.010 None 1.000 1 0 2018 2018
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.010 None 1.000 1 0 2011 2011
Entrez Id: 8988
Gene Symbol: HSPB3
HSPB3
Q12988 heat shock protein family B (small) member 3 327 0.448 0.769 6.1E-05 0.010 None 1.000 1 0 2017 2017
Entrez Id: 8829
Gene Symbol: NRP1
NRP1
O14786 neuropilin 1 246 0.476 0.808 0.99 0.010 None 1.000 1 0 2019 2019
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 Enzyme modulator 633 0.388 0.885 8.3E-03 0.010 None 1.000 1 0 2018 2018