Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.080 None 0.875 8 0 1998 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.060 None 1.000 6 0 2015 2019
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10 		H3 histone pseudogene 10 769 0.350 0.846 0.050 None 1.000 5 0 2017 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1 		Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.030 None 1.000 3 0 2017 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.020 None 1.000 2 0 2018 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.020 None 1.000 2 0 2018 2019
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.020 None 1.000 2 0 2001 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274 		Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.020 None 1.000 2 0 2017 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.020 None 1.000 2 0 2018 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.020 None 1.000 2 0 2018 2019
Entrez Id: 1630
Gene Symbol: DCC
DCC 		P43146 DCC netrin 1 receptor 279 0.471 0.808 0.99 0.020 None 1.000 2 0 2001 2006
Entrez Id: 55506
Gene Symbol: MACROH2A2
MACROH2A2 		Q9P0M6 macroH2A.2 histone Nucleic acid binding 15 0.780 0.192 0.98 0.010 None 1.000 1 0 2016 2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.010 None 1.000 1 0 2019 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A 		P11388 DNA topoisomerase II alpha 200 0.497 0.731 0.99 0.010 None 1.000 1 0 2017 2017
Entrez Id: 80316
Gene Symbol: PPP1R2C
PPP1R2C 		O14990 PPP1R2C family member C Enzyme modulator 231 0.478 0.846 0.010 None 1.000 1 0 2020 2020
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A 		O14497 AT-rich interaction domain 1A 341 0.455 0.846 1.00 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		Q14790 caspase 8 Enzyme 480 0.404 0.923 3.7E-06 0.010 None 1.000 1 0 2016 2016
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.010 None 1.000 1 0 2007 2007
Entrez Id: 1263
Gene Symbol: PLK3
PLK3 		Q9H4B4 polo like kinase 3 Kinase 52 0.644 0.538 1.9E-06 0.010 None 1.000 1 0 2016 2016
Entrez Id: 181
Gene Symbol: AGRP
AGRP 		O00253 agouti related neuropeptide Signaling 233 0.488 0.769 7.0E-04 0.010 None 1.000 1 0 2020 2020
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.010 None 1.000 1 0 2007 2007
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R 		P08069 insulin like growth factor 1 receptor Kinase 556 0.399 0.885 0.97 0.010 None 1.000 1 0 2019 2019