Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5979
Gene Symbol: RET
RET 		P07949 ret proto-oncogene Kinase 453 0.392 0.885 1.00 0.800 None 0.994 162 6 1991 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 888 0.319 0.846 1.00 0.600 None 0.990 197 2 2003 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.600 None 0.955 66 4 1991 2019
Entrez Id: 7253
Gene Symbol: TSHR
TSHR 		P16473 thyroid stimulating hormone receptor G-protein coupled receptor 187 0.486 0.808 3.0E-15 0.600 None 0.930 41 1 1992 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.590 None 1.000 9 0 1988 2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 457 0.378 0.885 8.0E-02 0.560 None 1.000 6 2 1988 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.500 strong 0.976 41 0 1997 2019
Entrez Id: 23405
Gene Symbol: DICER1
DICER1 		Q9UPY3 dicer 1, ribonuclease III Enzyme 271 0.446 0.846 1.00 0.450 None 1.000 5 0 2016 2019
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A 		P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 384 0.401 0.846 1.00 0.450 None 1.000 5 0 2002 2019
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5 		Q92911 solute carrier family 5 member 5 Transporter 167 0.499 0.769 2.9E-03 0.400 None 0.976 81 0 1997 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.400 None 0.977 43 1 2005 2019
Entrez Id: 7015
Gene Symbol: TERT
TERT 		O14746 telomerase reverse transcriptase Enzyme 525 0.374 0.846 0.99 0.400 None 1.000 29 2 2002 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 698 0.358 0.885 2.9E-02 0.400 None 1.000 22 0 2000 2018
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		P10145 C-X-C motif chemokine ligand 8 Signaling 1173 0.310 0.962 2.7E-04 0.400 None 0.909 10 0 2014 2019
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 765 0.343 0.885 1.00 0.380 None 1.000 8 0 2009 2018
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 748 0.344 0.923 0.89 0.380 None 1.000 8 1 1998 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 953 0.327 0.923 0.98 0.370 None 1.000 7 1 2003 2019
Entrez Id: 8031
Gene Symbol: NCOA4
NCOA4 		Q13772 nuclear receptor coactivator 4 Transcription factor 56 0.619 0.577 2.2E-06 0.370 None 1.000 7 0 1996 2015
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.360 None 1.000 6 0 2002 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2475 0.231 0.962 0.80 0.360 None 1.000 6 0 2003 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2132 0.248 0.962 0.32 0.350 None 0.833 5 0 2009 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 396 0.390 0.808 0.49 0.350 None 1.000 5 3 2010 2017
Entrez Id: 5909
Gene Symbol: RAP1GAP
RAP1GAP 		P47736 RAP1 GTPase activating protein Enzyme modulator 54 0.626 0.500 0.84 0.340 None 0.750 4 0 2010 2012
Entrez Id: 7170
Gene Symbol: TPM3
TPM3 		P06753 tropomyosin 3 Cellular structure 143 0.490 0.808 6.7E-03 0.340 None 1.000 4 0 2000 2019
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B 		P46527 cyclin dependent kinase inhibitor 1B 373 0.409 0.769 0.62 0.330 strong 1.000 3 0 2000 2010