Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		O60674 Janus kinase 2 Kinase 644 0.385 0.885 0.65 0.010 None 1.000 1 1 2012 2012
Entrez Id: 1515
Gene Symbol: CTSV
CTSV 		O60911 cathepsin V Enzyme 22 0.716 0.462 2.3E-07 0.010 None 1.000 1 0 2018 2018
Entrez Id: 8654
Gene Symbol: PDE5A
PDE5A 		O76074 phosphodiesterase 5A 187 0.513 0.731 1.1E-04 0.010 None 1.000 1 0 2010 2010
Entrez Id: 23576
Gene Symbol: DDAH1
DDAH1 		O94760 dimethylarginine dimethylaminohydrolase 1 Enzyme 73 0.604 0.615 2.8E-03 0.020 None 1.000 2 0 2010 2012
Entrez Id: 55937
Gene Symbol: APOM
APOM 		O95445 apolipoprotein M 82 0.590 0.769 9.6E-04 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 23564
Gene Symbol: DDAH2
DDAH2 		O95865 dimethylarginine dimethylaminohydrolase 2 Enzyme 36 0.670 0.538 1.4E-02 0.010 None 1.000 1 0 2012 2012
Entrez Id: 4513
Gene Symbol: COX2
COX2 		P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.010 None 1.000 1 0 2018 2018
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.020 None 1.000 2 0 2017 2020
Entrez Id: 2157
Gene Symbol: F8
F8 		P00451 coagulation factor VIII Enzyme 149 0.542 0.769 1.00 0.220 None 1.000 3 0 2005 2019
Entrez Id: 2147
Gene Symbol: F2
F2 		P00734 coagulation factor II, thrombin Enzyme 490 0.415 0.885 1.1E-03 0.300 None 1.000 17 2 1997 2016
Entrez Id: 2159
Gene Symbol: F10
F10 		P00742 coagulation factor X Enzyme 228 0.493 0.769 2.3E-06 0.200 None 1.000 1 0 2005 2005
Entrez Id: 2161
Gene Symbol: F12
F12 		P00748 coagulation factor XII Enzyme 87 0.612 0.577 8.3E-08 0.200 None 1.000 1 0 2005 2005
Entrez Id: 5972
Gene Symbol: REN
REN 		P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.010 None 1.000 1 0 2017 2017
Entrez Id: 183
Gene Symbol: AGT
AGT 		P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.020 None 1.000 2 0 2012 2018
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1 		P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 603 0.380 0.885 0.50 0.020 None 1.000 2 0 2006 2019
Entrez Id: 3949
Gene Symbol: LDLR
LDLR 		P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.010 None 1.000 1 1 2018 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.020 None 1.000 2 0 2006 2019
Entrez Id: 4803
Gene Symbol: NGF
NGF 		P01138 nerve growth factor Signaling 616 0.391 0.885 0.82 0.200 None 1.000 1 0 2010 2010
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.340 None 1.000 5 1 2003 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 1519 0.288 0.962 0.47 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.030 None 1.000 3 0 2017 2020
Entrez Id: 335
Gene Symbol: APOA1
APOA1 		P02647 apolipoprotein A1 416 0.429 0.885 5.5E-04 0.010 None 1.000 1 0 2016 2016
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.300 None 0.929 14 0 2004 2018
Entrez Id: 4155
Gene Symbol: MBP
MBP 		P02686 myelin basic protein 184 0.510 0.885 0.28 0.010 None 1.000 1 0 2002 2002
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.030 None 1.000 3 0 2006 2019