Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.600 None 0.972 40 0 1987 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.700 None 0.987 8 0 2001 2020
Entrez Id: 1440
Gene Symbol: CSF3
CSF3
P09919 colony stimulating factor 3 168 0.377 0.885 0.38 0.400 None 1.000 8 0 1993 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.400 None 0.974 6 0 1987 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.900 None 0.971 6 0 1982 2020
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 51 0.410 0.885 1.7E-05 0.400 None 0.978 5 0 1993 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.400 None 0.956 5 0 1998 2019
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 73 0.401 0.808 0.15 0.500 None 1.000 4 0 1991 2019
Entrez Id: 7431
Gene Symbol: VIM
VIM
P08670 vimentin 51 0.372 0.846 0.71 0.400 None 0.969 4 0 1989 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 270 0.248 0.962 0.32 0.400 None 0.961 4 0 1996 2020
Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A
P11388 DNA topoisomerase II alpha 24 0.497 0.731 0.99 0.400 None 0.971 4 0 1999 2019
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 Enzyme modulator 58 0.388 0.885 8.3E-03 0.400 None 0.963 4 0 1999 2019
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 285 0.379 0.923 0.15 0.400 None 0.898 4 0 1995 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 120 0.378 0.885 8.0E-02 0.600 None 0.919 4 0 1986 2016
Entrez Id: 9582
Gene Symbol: APOBEC3B
APOBEC3B
Q9UH17 apolipoprotein B mRNA editing enzyme catalytic subunit 3B Enzyme 21 0.547 0.731 5.2E-16 0.400 None 0.964 4 0 2010 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.400 None 0.959 3 0 1990 2020
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 67 0.425 0.846 0.72 0.400 None 0.914 3 0 1994 2019
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 82 0.400 0.923 1.1E-06 0.400 None 0.825 3 0 1997 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 231 0.276 0.962 0.13 0.400 None 0.982 3 0 1991 2020
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 45 0.357 0.923 8.5E-17 0.400 None 0.980 3 0 1985 2019
Entrez Id: 4288
Gene Symbol: MKI67
MKI67
P46013 marker of proliferation Ki-67 29 0.431 0.808 1.3E-28 0.400 None 1.000 3 0 1995 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 141 0.291 0.885 0.56 0.400 None 0.962 3 0 1994 2020
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
Q92731 estrogen receptor 2 Nuclear receptor 73 0.400 0.923 4.5E-08 0.400 None 0.969 3 0 1996 2020
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 Nucleic acid binding 65 0.444 0.885 1.00 0.600 None 0.962 3 0 1989 2020
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
P11362 fibroblast growth factor receptor 1 Kinase 87 0.362 0.885 1.00 0.600 None 0.977 2 0 1994 2020