Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.400 None 1.000 136 7 1996 2020
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.100 None 1.000 116 0 1996 2019
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
P08069 insulin like growth factor 1 receptor Kinase 556 0.399 0.885 0.97 0.400 None 1.000 95 5 1994 2019
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 Kinase 318 0.448 0.808 1.7E-15 0.400 None 1.000 94 0 1991 2019
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.500 None 1.000 81 7 1991 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.100 None 1.000 78 0 2011 2020
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2
P29323 EPH receptor B2 Kinase 649 0.374 0.846 1.00 0.100 None 1.000 71 0 1999 2019
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1
Q9NS23 Ras association domain family member 1 Enzyme modulator 400 0.420 0.808 4.9E-06 0.100 None 1.000 65 1 2001 2019
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.400 None 1.000 65 4 2003 2019
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.100 None 1.000 65 0 1998 2019
Entrez Id: 406947
Gene Symbol: MIR155
MIR155
microRNA 155 584 0.384 0.885 0.100 None 1.000 61 0 2008 2020
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.600 None 1.000 61 1 2004 2020
Entrez Id: 5744
Gene Symbol: PTHLH
PTHLH
P12272 parathyroid hormone like hormone 321 0.453 0.846 0.81 0.400 None 1.000 59 0 1992 2019
Entrez Id: 6935
Gene Symbol: ZEB1
ZEB1
P37275 zinc finger E-box binding homeobox 1 Transcription factor 310 0.442 0.808 0.97 0.400 None 1.000 58 0 2007 2019
Entrez Id: 3320
Gene Symbol: HSP90AA1
HSP90AA1
P07900 heat shock protein 90 alpha family class A member 1 Chaperone 455 0.411 0.923 0.86 0.400 None 1.000 57 0 1992 2020
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 317 0.455 0.846 1.00 0.500 None 1.000 53 8 1995 2019
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.100 None 1.000 52 0 1994 2019
Entrez Id: 2305
Gene Symbol: FOXM1
FOXM1
Q08050 forkhead box M1 323 0.441 0.769 7.4E-04 0.400 None 1.000 52 0 2005 2020
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
P27361 mitogen-activated protein kinase 3 Kinase 647 0.379 0.885 3.7E-02 0.100 None 1.000 50 0 2000 2020
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
Q16539 mitogen-activated protein kinase 14 Kinase 626 0.379 0.923 0.37 0.100 None 1.000 48 0 2000 2019
Entrez Id: 406985
Gene Symbol: MIR200C
MIR200C
microRNA 200c 202 0.486 0.846 0.400 None 1.000 48 0 2010 2020
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.400 None 1.000 47 2 1992 2019
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase Enzyme 439 0.425 0.923 2.3E-06 0.100 None 1.000 47 0 1987 2019
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 Signaling 724 0.365 0.962 1.4E-03 0.400 None 1.000 46 0 1997 2020
Entrez Id: 406903
Gene Symbol: MIR10B
MIR10B
microRNA 10b 167 0.509 0.808 0.400 None 1.000 44 0 2007 2019