Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 457 0.378 0.885 8.0E-02 0.700 None 1.000 28 1 1983 2018
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
P22607 fibroblast growth factor receptor 3 Kinase 377 0.391 0.846 1.6E-05 0.500 None 0.979 93 2 2001 2019
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 283 0.420 0.846 7.1E-20 0.400 None 1.000 19 4 2001 2014
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 765 0.343 0.885 1.00 0.400 None 1.000 14 2 2009 2020
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
Q92574 TSC complex subunit 1 248 0.440 0.808 1.00 0.400 None 0.857 14 0 1999 2019
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 563 0.374 0.885 5.6E-47 0.390 None 1.000 9 1 2008 2017
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 581 0.369 0.885 1.00 0.370 None 1.000 7 0 2013 2019
Entrez Id: 10735
Gene Symbol: STAG2
STAG2
Q8N3U4 stromal antigen 2 Nucleic acid binding 52 0.568 0.731 1.00 0.360 None 1.000 6 0 2013 2018
Entrez Id: 7403
Gene Symbol: KDM6A
KDM6A
O15550 lysine demethylase 6A Epigenetic regulator 127 0.498 0.769 1.00 0.360 None 1.000 6 0 2011 2017
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 Kinase 263 0.448 0.808 1.7E-15 0.340 None 1.000 4 0 2013 2018
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
Q04721 notch receptor 2 202 0.441 0.808 1.00 0.330 None 1.000 3 0 2016 2019
Entrez Id: 4194
Gene Symbol: MDM4
MDM4
O15151 MDM4 regulator of p53 Nucleic acid binding 252 0.461 0.808 1.00 0.320 None 1.000 2 0 2014 2016
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 Nucleic acid binding 220 0.444 0.885 1.00 0.310 None 1.000 1 0 2002 2002
Entrez Id: 8000
Gene Symbol: PSCA
PSCA
O43653 prostate stem cell antigen 103 0.555 0.615 0.17 0.200 None 1.000 20 6 2000 2019
Entrez Id: 10460
Gene Symbol: TACC3
TACC3
Q9Y6A5 transforming acidic coiled-coil containing protein 3 55 0.615 0.615 2.7E-07 0.170 None 1.000 7 1 2010 2018
Entrez Id: 6563
Gene Symbol: SLC14A1
SLC14A1
Q13336 solute carrier family 14 member 1 (Kidd blood group) Transporter 27 0.678 0.538 5.8E-14 0.160 None 1.000 6 2 2011 2017
Entrez Id: 100270680
Gene Symbol: CASC11
CASC11
cancer susceptibility 11 39 0.641 0.577 0.120 None 1.000 2 1 2008 2019
Entrez Id: 55824
Gene Symbol: PAG1
PAG1
Q9NWQ8 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 173 0.505 0.808 1.8E-02 0.120 None 1.000 2 0 2012 2019
Entrez Id: 10283
Gene Symbol: CWC27
CWC27
Q6UX04 CWC27 spliceosome associated cyclophilin Enzyme 4 0.722 0.346 4.6E-07 0.110 None 1.000 1 1 2016 2016
Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 42 0.617 0.615 1.6E-02 0.110 None 1.000 1 0 2008 2014
Entrez Id: 55892
Gene Symbol: MYNN
MYNN
Q9NPC7 myoneurin 3 0.722 0.423 0.57 0.110 None 1.000 1 1 2014 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.100 None 0.978 228 6 1991 2020
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 581 0.380 0.923 2.1E-03 0.100 None 0.935 108 2 1993 2019
Entrez Id: 10
Gene Symbol: NAT2
NAT2
P11245 N-acetyltransferase 2 Enzyme 273 0.451 0.885 3.3E-06 0.100 None 0.937 95 2 1995 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.100 None 1.000 70 1 1989 2020