Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.800 strong 0.977 664 600 1975 2020
Entrez Id: 2053
Gene Symbol: EPHX2
EPHX2
P34913 epoxide hydrolase 2 Enzyme 97 0.568 0.654 1.8E-21 0.610 None 1.000 1 1 2004 2004
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.600 None 0.889 18 6 1989 2020
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
O95477 ATP binding cassette subfamily A member 1 Transporter 291 0.467 0.846 1.5E-13 0.520 limited 1.000 3 0 2005 2019
Entrez Id: 336
Gene Symbol: APOA2
APOA2
P02652 apolipoprotein A2 Transporter 77 0.582 0.769 4.5E-02 0.510 None 1.000 1 0 2002 2002
Entrez Id: 2690
Gene Symbol: GHR
GHR
P10912 growth hormone receptor Signaling 247 0.490 0.846 8.4E-05 0.510 None 1.000 1 1 2003 2003
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 339 0.453 0.808 1.9E-16 0.500 None 0.992 130 8 1988 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.390 None 1.000 10 2 2000 2019
Entrez Id: 4023
Gene Symbol: LPL
LPL
P06858 lipoprotein lipase Enzyme 290 0.474 0.808 1.3E-09 0.380 None 1.000 9 3 1993 2016
Entrez Id: 1071
Gene Symbol: CETP
CETP
P11597 cholesteryl ester transfer protein 188 0.512 0.731 1.2E-23 0.360 None 1.000 7 1 1997 2011
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
P04035 3-hydroxy-3-methylglutaryl-CoA reductase 154 0.529 0.692 1.00 0.340 None 1.000 5 1 1983 2016
Entrez Id: 5445
Gene Symbol: PON2
PON2
Q15165 paraoxonase 2 117 0.566 0.808 5.4E-05 0.320 None 1.000 3 1 2001 2006
Entrez Id: 337
Gene Symbol: APOA4
APOA4
P06727 apolipoprotein A4 88 0.582 0.577 5.5E-06 0.310 None 1.000 2 0 1998 2005
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
P11150 lipase C, hepatic type Enzyme 120 0.585 0.654 3.3E-07 0.310 None 1.000 2 0 2005 2014
Entrez Id: 345
Gene Symbol: APOC3
APOC3
P02656 apolipoprotein C3 153 0.531 0.731 1.0E-02 0.300 None 1.000 1 0 2005 2005
Entrez Id: 10842
Gene Symbol: PPP1R17
PPP1R17
O96001 protein phosphatase 1 regulatory subunit 17 9 0.805 0.192 1.0E-03 0.300 None 0 0
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 257 0.482 0.808 2.7E-17 0.200 None 0.971 175 7 2003 2020
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) Enzyme 340 0.444 0.769 6.6E-89 0.100 None 0.973 37 1 1991 2019
Entrez Id: 26119
Gene Symbol: LDLRAP1
LDLRAP1
Q5SW96 low density lipoprotein receptor adaptor protein 1 Signaling 64 0.641 0.538 6.5E-06 0.100 None 1.000 12 1 2002 2019
Entrez Id: 102465534
Gene Symbol: MIR6886
MIR6886
microRNA 6886 6 0.861 0.077 0.100 None 0 132
Entrez Id: 4607
Gene Symbol: MYBPC3
MYBPC3
Q14896 myosin binding protein C3 100 0.593 0.385 8.0E-11 0.080 None 0.875 8 1 1977 2005
Entrez Id: 7168
Gene Symbol: TPM1
TPM1
P09493 tropomyosin 1 Cellular structure 117 0.560 0.615 1.0E-03 0.070 None 1.000 7 3 1994 2012
Entrez Id: 4625
Gene Symbol: MYH7
MYH7
P12883 myosin heavy chain 7 257 0.516 0.692 4.2E-16 0.060 None 1.000 6 0 1994 2005
Entrez Id: 335
Gene Symbol: APOA1
APOA1
P02647 apolipoprotein A1 416 0.429 0.885 5.5E-04 0.060 None 1.000 6 0 1998 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.060 None 1.000 6 0 1994 2015