Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2 		P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 91 0.529 0.808 1.00 0.520 None 0.750 2 0 2002 2014
Entrez Id: 183
Gene Symbol: AGT
AGT 		P01019 angiotensinogen Enzyme modulator 632 0.367 0.923 5.0E-08 0.330 None 1.000 3 0 2013 2018
Entrez Id: 335
Gene Symbol: APOA1
APOA1 		P02647 apolipoprotein A1 322 0.429 0.885 5.5E-04 0.310 None 1.000 1 0 2008 2008
Entrez Id: 6696
Gene Symbol: SPP1
SPP1 		P10451 secreted phosphoprotein 1 715 0.353 0.885 2.1E-06 0.310 None 1.000 1 0 2007 2015
Entrez Id: 3816
Gene Symbol: KLK1
KLK1 		P06870 kallikrein 1 Enzyme 118 0.533 0.769 1.5E-04 0.310 None 1.000 1 0 2004 2005
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 739 0.357 0.885 3.6E-03 0.300 None 1.000 10 0 2013 2019
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3 		P27361 mitogen-activated protein kinase 3 Kinase 577 0.379 0.885 3.7E-02 0.230 None 1.000 3 0 2015 2017
Entrez Id: 59272
Gene Symbol: ACE2
ACE2 		Q9BYF1 angiotensin I converting enzyme 2 Enzyme 238 0.477 0.769 1.00 0.230 None 1.000 3 0 2012 2019
Entrez Id: 5465
Gene Symbol: PPARA
PPARA 		Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 346 0.432 0.885 3.0E-02 0.230 None 1.000 3 0 2009 2018
Entrez Id: 5350
Gene Symbol: PLN
PLN 		P26678 phospholamban 60 0.595 0.577 0.45 0.220 None 1.000 2 0 2010 2012
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 935 0.330 0.923 1.00 0.220 None 1.000 2 0 2015 2019
Entrez Id: 846
Gene Symbol: CASR
CASR 		P41180 calcium sensing receptor G-protein coupled receptor 432 0.410 0.846 4.7E-02 0.210 None 1.000 1 0 2012 2018
Entrez Id: 4878
Gene Symbol: NPPA
NPPA 		P01160 natriuretic peptide A 144 0.505 0.769 5.5E-04 0.210 None 1.000 1 0 2013 2015
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.210 None 1.000 1 0 2016 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE 		P12821 angiotensin I converting enzyme Enzyme 979 0.328 0.923 1.0E-37 0.210 None 1.000 1 0 2012 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1294 0.291 0.885 0.56 0.210 None 1.000 1 0 2011 2018
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		P09601 heme oxygenase 1 510 0.381 0.923 9.7E-03 0.210 None 1.000 1 0 2013 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		Q96EB6 sirtuin 1 Epigenetic regulator 611 0.378 0.885 8.7E-02 0.100 None 1.000 10 0 2017 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 702 0.361 0.962 8.1E-04 0.090 None 1.000 9 0 2017 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		Q06546 GA binding protein transcription factor subunit alpha Transcription factor 630 0.379 0.885 1.00 0.080 None 1.000 8 0 2016 2019
Entrez Id: 4485
Gene Symbol: MST1
MST1 		P26927 macrophage stimulating 1 Enzyme 224 0.465 0.885 4.8E-19 0.050 None 1.000 5 0 2017 2020
Entrez Id: 26291
Gene Symbol: FGF21
FGF21 		Q9NSA1 fibroblast growth factor 21 Signaling 217 0.485 0.769 2.9E-02 0.040 None 1.000 4 0 2017 2019
Entrez Id: 5562
Gene Symbol: PRKAA1
PRKAA1 		Q13131 protein kinase AMP-activated catalytic subunit alpha 1 Kinase 313 0.453 0.846 0.14 0.040 None 1.000 4 0 2017 2019
Entrez Id: 23410
Gene Symbol: SIRT3
SIRT3 		Q9NTG7 sirtuin 3 Epigenetic regulator 216 0.488 0.731 1.6E-04 0.030 None 1.000 3 0 2017 2019
Entrez Id: 10984
Gene Symbol: KCNQ1OT1
KCNQ1OT1 		KCNQ1 opposite strand/antisense transcript 1 112 0.534 0.731 0.030 None 1.000 3 0 2018 2020