Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2053
Gene Symbol: EPHX2
EPHX2
P34913 epoxide hydrolase 2 Enzyme 97 0.568 0.654 1.8E-21 0.010 None < 0.001 1 0 2011 2011
Entrez Id: 50507
Gene Symbol: NOX4
NOX4
Q9NPH5 NADPH oxidase 4 Enzyme 260 0.471 0.885 5.8E-20 0.010 None 1.000 1 0 2017 2017
Entrez Id: 1585
Gene Symbol: CYP11B2
CYP11B2
P19099 cytochrome P450 family 11 subfamily B member 2 142 0.553 0.615 7.1E-19 0.010 None 1.000 1 0 2010 2010
Entrez Id: 7060
Gene Symbol: THBS4
THBS4
P35443 thrombospondin 4 59 0.644 0.654 1.5E-18 0.010 None 1.000 1 0 2011 2011
Entrez Id: 10392
Gene Symbol: NOD1
NOD1
Q9Y239 nucleotide binding oligomerization domain containing 1 Enzyme 136 0.541 0.769 2.5E-18 0.030 None 1.000 3 0 2011 2016
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.010 None 1.000 1 0 2018 2018
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 257 0.482 0.808 2.7E-17 0.030 None 1.000 3 0 2017 2019
Entrez Id: 1361
Gene Symbol: CPB2
CPB2
Q96IY4 carboxypeptidase B2 Enzyme 148 0.536 0.846 2.7E-17 0.010 None 1.000 1 0 2003 2003
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1
Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 404 0.446 0.885 1.0E-16 0.010 None 1.000 1 0 2019 2019
Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4
Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 422 0.457 0.808 2.2E-16 0.010 None 1.000 1 0 2016 2016
Entrez Id: 8751
Gene Symbol: ADAM15
ADAM15
Q13444 ADAM metallopeptidase domain 15 Enzyme 59 0.626 0.577 2.4E-16 0.010 None 1.000 1 0 2019 2019
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.030 None 1.000 3 1 2010 2019
Entrez Id: 1118
Gene Symbol: CHIT1
CHIT1
Q13231 chitinase 1 142 0.525 0.692 7.2E-16 0.010 None 1.000 1 0 2017 2017
Entrez Id: 350
Gene Symbol: APOH
APOH
P02749 apolipoprotein H 121 0.563 0.769 1.6E-15 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1573
Gene Symbol: CYP2J2
CYP2J2
P51589 cytochrome P450 family 2 subfamily J member 2 65 0.628 0.615 1.6E-15 0.010 None 1.000 1 0 2015 2015
Entrez Id: 3026
Gene Symbol: HABP2
HABP2
Q14520 hyaluronan binding protein 2 Enzyme 88 0.593 0.615 2.0E-15 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7253
Gene Symbol: TSHR
TSHR
P16473 thyroid stimulating hormone receptor G-protein coupled receptor 250 0.486 0.808 3.0E-15 0.010 None 1.000 1 0 2019 2019
Entrez Id: 27352
Gene Symbol: SGSM3
SGSM3
Q96HU1 small G protein signaling modulator 3 Enzyme 259 0.469 0.808 3.4E-15 0.010 None 1.000 1 0 2017 2017
Entrez Id: 308
Gene Symbol: ANXA5
ANXA5
P08758 annexin A5 283 0.458 0.769 3.8E-15 0.010 None 1.000 1 0 2015 2015
Entrez Id: 3689
Gene Symbol: ITGB2
ITGB2
P05107 integrin subunit beta 2 Receptor 340 0.444 0.923 5.1E-15 0.010 None 1.000 1 0 2019 2019
Entrez Id: 11093
Gene Symbol: ADAMTS13
ADAMTS13
Q76LX8 ADAM metallopeptidase with thrombospondin type 1 motif 13 Enzyme 229 0.496 0.769 5.1E-15 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4353
Gene Symbol: MPO
MPO
P05164 myeloperoxidase Enzyme 653 0.377 0.923 7.1E-15 0.040 None 1.000 4 0 2016 2019
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
O15553 MEFV innate immuity regulator, pyrin 410 0.440 0.885 1.0E-14 0.010 None 1.000 1 0 2017 2017
Entrez Id: 2677
Gene Symbol: GGCX
GGCX
P38435 gamma-glutamyl carboxylase 56 0.678 0.538 2.0E-14 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2006
Gene Symbol: ELN
ELN
P15502 elastin 545 0.415 0.885 2.1E-14 0.020 None 1.000 2 0 2013 2015