Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7276
Gene Symbol: TTR
TTR 		P02766 transthyretin Transporter 404 0.423 0.885 0.52 0.100 None 1.000 11 1 1994 2019
Entrez Id: 6622
Gene Symbol: SNCA
SNCA 		P37840 synuclein alpha Transporter 367 0.427 0.885 0.88 0.050 None 0.800 5 0 2007 2020
Entrez Id: 8929
Gene Symbol: PHOX2B
PHOX2B 		Q99453 paired like homeobox 2B 89 0.565 0.731 0.94 0.050 None 1.000 5 1 2005 2008
Entrez Id: 4204
Gene Symbol: MECP2
MECP2 		P51608 methyl-CpG binding protein 2 Epigenetic regulator 324 0.414 0.846 0.89 0.030 None 1.000 3 0 2004 2017
Entrez Id: 2047
Gene Symbol: EPHB1
EPHB1 		P54762 EPH receptor B1 Kinase 153 0.518 0.846 1.00 0.020 None 1.000 2 0 2003 2008
Entrez Id: 4001
Gene Symbol: LMNB1
LMNB1 		P20700 lamin B1 78 0.564 0.731 0.55 0.020 None 1.000 2 0 2009 2013
Entrez Id: 1621
Gene Symbol: DBH
DBH 		P09172 dopamine beta-hydroxylase 152 0.511 0.846 3.3E-10 0.020 None 0.500 2 0 2002 2003
Entrez Id: 5972
Gene Symbol: REN
REN 		P00797 renin Enzyme 668 0.370 0.923 2.4E-07 0.020 None 1.000 2 0 2014 2019
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2 		P23975 solute carrier family 6 member 2 Transporter 202 0.490 0.846 8.2E-02 0.020 None 1.000 2 1 2003 2008
Entrez Id: 65125
Gene Symbol: WNK1
WNK1 		Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 407 0.416 0.846 1.00 0.020 None 1.000 2 0 2012 2016
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2 		O15123 angiopoietin 2 Signaling 420 0.410 0.846 0.83 0.020 None 1.000 2 0 2011 2017
Entrez Id: 2004
Gene Symbol: ELK3
ELK3 		P41970 ETS transcription factor ELK3 Transcription factor 212 0.490 0.846 8.4E-02 0.020 None 1.000 2 0 2003 2008
Entrez Id: 4287
Gene Symbol: ATXN3
ATXN3 		P54252 ataxin 3 Enzyme 151 0.521 0.808 0.11 0.020 None 1.000 2 0 1997 2004
Entrez Id: 6335
Gene Symbol: SCN9A
SCN9A 		Q15858 sodium voltage-gated channel alpha subunit 9 Ion channel 69 0.543 0.615 4.8E-19 0.020 None 1.000 2 1 2013 2014
Entrez Id: 8086
Gene Symbol: AAAS
AAAS 		Q9NRG9 aladin WD repeat nucleoporin 48 0.601 0.654 2.4E-13 0.020 None 1.000 2 1 2005 2019
Entrez Id: 738
Gene Symbol: VPS51
VPS51 		Q9UID3 VPS51 subunit of GARP complex 292 0.452 0.846 1.1E-08 0.020 None 1.000 2 0 2011 2017
Entrez Id: 7173
Gene Symbol: TPO
TPO 		P07202 thyroid peroxidase Enzyme 277 0.455 0.846 1.8E-21 0.020 None 1.000 2 0 2017 2019
Entrez Id: 5967
Gene Symbol: REG1A
REG1A 		P05451 regenerating family member 1 alpha 257 0.467 0.846 1.3E-05 0.010 None 1.000 1 0 2019 2019
Entrez Id: 57091
Gene Symbol: CASS4
CASS4 		Q9NQ75 Cas scaffold protein family member 4 12 0.722 0.231 0.37 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5723
Gene Symbol: PSPH
PSPH 		P78330 phosphoserine phosphatase Enzyme 82 0.570 0.808 9.7E-04 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5623
Gene Symbol: PSPN
PSPN 		O60542 persephin Signaling 70 0.608 0.769 1.1E-04 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3 		P27361 mitogen-activated protein kinase 3 Kinase 577 0.379 0.885 3.7E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1 		Q8TD31 coiled-coil alpha-helical rod protein 1 175 0.505 0.808 1.0E-16 0.010 None 1.000 1 0 2019 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 852 0.345 0.923 0.66 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5818
Gene Symbol: NECTIN1
NECTIN1 		Q15223 nectin cell adhesion molecule 1 101 0.523 0.808 6.1E-02 0.010 None 1.000 1 0 2019 2019