Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 182 0.305 0.923 0.26 0.800 strong 0.952 3 3 1972 2019
Entrez Id: 3621
Gene Symbol: ING1
ING1 		Q9UK53 inhibitor of growth family member 1 Nucleic acid binding 12 0.573 0.692 9.7E-03 0.710 None 1.000 1 3 2000 2000
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 115 0.300 0.885 0.39 0.500 None 0.983 3 7 1994 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.500 None 0.973 2 80 1991 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.500 None 1.000 1 29 2001 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.500 None 0.982 0 4 1992 2020
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 89 0.357 0.885 3.6E-03 0.440 None 1.000 0 5 2013 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 96 0.344 0.923 0.89 0.400 None 1.000 2 0 1994 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 138 0.320 0.923 1.00 0.400 None 0.957 1 0 2000 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.400 None 0.966 1 0 1999 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 109 0.311 0.962 0.98 0.400 None 1.000 1 0 2005 2020
Entrez Id: 4233
Gene Symbol: MET
MET 		P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 90 0.380 0.846 0.97 0.400 None 0.933 0 0 2000 2020
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		P46531 notch receptor 1 78 0.369 0.885 1.00 0.400 None 1.000 0 0 2011 2019
Entrez Id: 1019
Gene Symbol: CDK4
CDK4 		P11802 cyclin dependent kinase 4 Kinase 37 0.412 0.808 6.3E-02 0.390 None 1.000 1 0 1995 2019
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		P16455 O-6-methylguanine-DNA methyltransferase 26 0.412 0.885 1.2E-07 0.390 None 0.800 1 0 2004 2019
Entrez Id: 10413
Gene Symbol: YAP1
YAP1 		P46937 Yes associated protein 1 Enzyme modulator 31 0.432 0.808 1.00 0.380 None 1.000 1 0 2010 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		P05019 insulin like growth factor 1 119 0.318 0.885 0.27 0.370 None 1.000 1 0 2006 2018
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		Q14790 caspase 8 Enzyme 58 0.404 0.923 3.7E-06 0.360 None 1.000 1 0 2009 2016
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		P01583 interleukin 1 alpha 70 0.333 0.962 1.6E-04 0.360 None 1.000 1 0 1996 2019
Entrez Id: 7465
Gene Symbol: WEE1
WEE1 		P30291 WEE1 G2 checkpoint kinase Kinase 1 0.545 0.769 1.00 0.360 None 1.000 1 0 2014 2019
Entrez Id: 1017
Gene Symbol: CDK2
CDK2 		P24941 cyclin dependent kinase 2 Kinase 6 0.456 0.692 0.61 0.340 None 0.800 1 0 1994 2018
Entrez Id: 8900
Gene Symbol: CCNA1
CCNA1 		P78396 cyclin A1 Enzyme modulator 3 0.588 0.654 4.3E-04 0.330 None 1.000 2 0 2004 2018
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		P04179 superoxide dismutase 2 Enzyme 285 0.379 0.923 0.15 0.330 None 1.000 1 0 2007 2017
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1 		P33527 ATP binding cassette subfamily C member 1 Transporter 20 0.445 0.808 1.2E-03 0.330 None 1.000 1 0 2000 2017
Entrez Id: 3236
Gene Symbol: HOXD10
HOXD10 		P28358 homeobox D10 15 0.590 0.538 6.3E-02 0.320 None 1.000 1 0 2012 2014