Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.100 None 0.945 271 0 1995 2020
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.100 None 1.000 18 0 2002 2019
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		P49768 presenilin 1 Enzyme 369 0.469 0.846 0.97 0.070 None 1.000 7 2 2002 2019
Entrez Id: 27240
Gene Symbol: SIT1
SIT1 		Q9Y3P8 signaling threshold regulating transmembrane adaptor 1 29 0.682 0.615 9.6E-04 0.010 None 1.000 1 0 2002 2002
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		P06276 butyrylcholinesterase 392 0.447 0.923 1.1E-13 0.100 None 0.857 14 0 2003 2020
Entrez Id: 351
Gene Symbol: APP
APP 		P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.400 None 1.000 12 0 2003 2019
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2 		P49810 presenilin 2 Enzyme 146 0.550 0.654 5.4E-04 0.040 None 1.000 4 1 2003 2019
Entrez Id: 3077
Gene Symbol: HFE
HFE 		Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.030 None 1.000 3 0 2003 2018
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.020 None 1.000 2 3 2003 2015
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.020 None 0.500 2 1 2004 2011
Entrez Id: 4311
Gene Symbol: MME
MME 		P08473 membrane metalloendopeptidase Enzyme 470 0.407 0.808 1.5E-18 0.010 None 1.000 1 0 2005 2005
Entrez Id: 54840
Gene Symbol: APTX
APTX 		Q7Z2E3 aprataxin Nucleic acid binding 94 0.590 0.500 4.0E-10 0.010 None 1.000 1 1 2005 2005
Entrez Id: 246
Gene Symbol: ALOX15
ALOX15 		P16050 arachidonate 15-lipoxygenase Enzyme 205 0.502 0.846 1.1E-23 0.010 None 1.000 1 0 2005 2005
Entrez Id: 780
Gene Symbol: DDR1
DDR1 		Q08345 discoidin domain receptor tyrosine kinase 1 Kinase 195 0.497 0.808 4.6E-06 0.010 None 1.000 1 0 2005 2005
Entrez Id: 1471
Gene Symbol: CST3
CST3 		P01034 cystatin C 370 0.436 0.808 3.9E-03 0.060 None 1.000 6 0 2006 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.040 None 1.000 4 0 2006 2018
Entrez Id: 10858
Gene Symbol: CYP46A1
CYP46A1 		Q9Y6A2 cytochrome P450 family 46 subfamily A member 1 Enzyme 39 0.659 0.500 0.99 0.030 None 1.000 3 1 2006 2012
Entrez Id: 5300
Gene Symbol: PIN1
PIN1 		Q13526 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 212 0.488 0.769 0.74 0.030 None 1.000 3 0 2006 2007
Entrez Id: 4923
Gene Symbol: NTSR1
NTSR1 		P30989 neurotensin receptor 1 G-protein coupled receptor 124 0.563 0.692 1.9E-08 0.020 None 1.000 2 0 2006 2007
Entrez Id: 51083
Gene Symbol: GAL
GAL 		P22466 galanin and GMAP prepropeptide 226 0.493 0.846 4.4E-06 0.020 None 1.000 2 0 2006 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.100 None 0.886 35 3 2007 2020
Entrez Id: 4803
Gene Symbol: NGF
NGF 		P01138 nerve growth factor Signaling 616 0.391 0.885 0.82 0.070 None 1.000 7 0 2007 2019
Entrez Id: 1103
Gene Symbol: CHAT
CHAT 		P28329 choline O-acetyltransferase Enzyme 230 0.520 0.808 5.6E-11 0.020 None 1.000 2 0 2007 2008
Entrez Id: 1137
Gene Symbol: CHRNA4
CHRNA4 		P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 248 0.492 0.808 8.5E-05 0.020 None 1.000 2 0 2007 2020
Entrez Id: 948
Gene Symbol: CD36
CD36 		P16671 CD36 molecule Receptor 351 0.446 0.846 1.1E-60 0.010 None 1.000 1 0 2007 2007