Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.100 None 1.000 22 0 1994 2019
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.100 None 1.000 16 0 2001 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.070 None 0.857 7 3 2013 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.050 None 1.000 5 0 1994 2018
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.040 None 1.000 4 0 2018 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.040 None 1.000 4 0 2013 2019
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 Kinase 318 0.448 0.808 1.7E-15 0.030 None 1.000 3 0 2014 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.030 None 1.000 3 0 2009 2014
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.030 None 0.667 3 0 2018 2019
Entrez Id: 8091
Gene Symbol: HMGA2
HMGA2
P52926 high mobility group AT-hook 2 Nucleic acid binding 382 0.429 0.808 0.87 0.030 None 0.667 3 0 2013 2016
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.020 None 1.000 2 0 2018 2019
Entrez Id: 5324
Gene Symbol: PLAG1
PLAG1
Q6DJT9 PLAG1 zinc finger Transcription factor 219 0.493 0.808 1.00 0.020 None 1.000 2 0 2013 2016
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
P12004 proliferating cell nuclear antigen Nucleic acid binding 581 0.382 0.846 0.98 0.010 None 1.000 1 0 1996 1996
Entrez Id: 4085
Gene Symbol: MAD2L1
MAD2L1
Q13257 mitotic arrest deficient 2 like 1 98 0.575 0.615 9.3E-03 0.010 None 1.000 1 0 2010 2010
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.010 None 1.000 1 1 2013 2013
Entrez Id: 55364
Gene Symbol: IMPACT
IMPACT
Q9P2X3 impact RWD domain protein 85 0.593 0.808 4.8E-08 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.010 None 1.000 1 0 2013 2013
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.010 None 1.000 1 0 2013 2013
Entrez Id: 5818
Gene Symbol: NECTIN1
NECTIN1
Q15223 nectin cell adhesion molecule 1 196 0.523 0.808 6.1E-02 0.010 None 1.000 1 0 2013 2013
Entrez Id: 898
Gene Symbol: CCNE1
CCNE1
P24864 cyclin E1 Enzyme modulator 133 0.538 0.731 0.97 0.010 None 1.000 1 0 2019 2019
Entrez Id: 896
Gene Symbol: CCND3
CCND3
P30281 cyclin D3 Enzyme modulator 126 0.554 0.654 0.98 0.010 None 1.000 1 0 2013 2013
Entrez Id: 843
Gene Symbol: CASP10
CASP10
Q92851 caspase 10 Enzyme 166 0.528 0.692 4.6E-12 0.010 None 1.000 1 0 2005 2005
Entrez Id: 8031
Gene Symbol: NCOA4
NCOA4
Q13772 nuclear receptor coactivator 4 Transcription factor 62 0.619 0.577 2.2E-06 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7809
Gene Symbol: BSND
BSND
Q8WZ55 barttin CLCNK type accessory subunit beta 91 0.603 0.692 1.1E-10 0.010 None 1.000 1 0 2018 2018
Entrez Id: 701
Gene Symbol: BUB1B
BUB1B
O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 231 0.502 0.808 7.0E-10 0.010 None 1.000 1 0 2010 2010