Entrez Id: |
4436 |
Gene Symbol: |
MSH2 |
MSH2
|
P43246
|
mutS homolog 2
|
Nucleic acid binding
|
490
|
0.406 |
0.808 |
0.90 |
1.000 |
definitive
|
0.983 |
600
|
464
|
1993 |
2020 |
Entrez Id: |
4292 |
Gene Symbol: |
MLH1 |
MLH1
|
P40692
|
mutL homolog 1
|
Nucleic acid binding
|
526
|
0.399 |
0.808 |
3.4E-05 |
0.900 |
None
|
0.977 |
652
|
519
|
1975 |
2020 |
Entrez Id: |
2956 |
Gene Symbol: |
MSH6 |
MSH6
|
P52701
|
mutS homolog 6
|
Nucleic acid binding
|
296
|
0.462 |
0.731 |
3.7E-05 |
0.800 |
definitive
|
0.987 |
306
|
240
|
1988 |
2020 |
Entrez Id: |
5395 |
Gene Symbol: |
PMS2 |
PMS2
|
P54278
|
PMS1 homolog 2, mismatch repair system component
|
Nucleic acid binding
|
244
|
0.484 |
0.808 |
4.5E-27 |
0.800 |
definitive
|
0.979 |
191
|
81
|
1994 |
2020 |
Entrez Id: |
4072 |
Gene Symbol: |
EPCAM |
EPCAM
|
P16422
|
epithelial cell adhesion molecule
|
|
328
|
0.451 |
0.885 |
1.3E-07 |
0.700 |
None
|
1.000 |
36
|
1
|
2009 |
2019 |
Entrez Id: |
27030 |
Gene Symbol: |
MLH3 |
MLH3
|
Q9UHC1
|
mutL homolog 3
|
Nucleic acid binding
|
108
|
0.582 |
0.538 |
4.9E-08 |
0.700 |
moderate
|
0.933 |
15
|
0
|
2001 |
2019 |
Entrez Id: |
7048 |
Gene Symbol: |
TGFBR2 |
TGFBR2
|
P37173
|
transforming growth factor beta receptor 2
|
Kinase
|
502
|
0.413 |
0.846 |
0.13 |
0.600 |
None
|
1.000 |
11
|
0
|
1995 |
2018 |
Entrez Id: |
22909 |
Gene Symbol: |
FAN1 |
FAN1
|
Q9Y2M0
|
FANCD2 and FANCI associated nuclease 1
|
|
93
|
0.610 |
0.577 |
1.7E-25 |
0.500 |
limited
|
1.000 |
4
|
0
|
2010 |
2016 |
Entrez Id: |
324 |
Gene Symbol: |
APC |
APC
|
P25054
|
APC regulator of WNT signaling pathway
|
|
703
|
0.373 |
0.962 |
1.00 |
0.400 |
None
|
0.931 |
29
|
6
|
1992 |
2018 |
Entrez Id: |
5378 |
Gene Symbol: |
PMS1 |
PMS1
|
P54277
|
PMS1 homolog 1, mismatch repair system component
|
Nucleic acid binding
|
115
|
0.569 |
0.654 |
1.3E-17 |
0.400 |
None
|
1.000 |
20
|
0
|
1994 |
2017 |
Entrez Id: |
3845 |
Gene Symbol: |
KRAS |
KRAS
|
P01116
|
KRAS proto-oncogene, GTPase
|
Enzyme modulator
|
1213
|
0.320 |
0.923 |
7.9E-04 |
0.400 |
None
|
0.917 |
12
|
0
|
1996 |
2017 |
Entrez Id: |
4437 |
Gene Symbol: |
MSH3 |
MSH3
|
P20585
|
mutS homolog 3
|
Nucleic acid binding
|
245
|
0.474 |
0.769 |
7.4E-31 |
0.390 |
limited
|
0.857 |
14
|
0
|
1996 |
2018 |
Entrez Id: |
9156 |
Gene Symbol: |
EXO1 |
EXO1
|
Q9UQ84
|
exonuclease 1
|
Enzyme
|
87
|
0.578 |
0.692 |
8.1E-13 |
0.350 |
disputed
|
0.778 |
9
|
0
|
2000 |
2016 |
Entrez Id: |
79728 |
Gene Symbol: |
PALB2 |
PALB2
|
Q86YC2
|
partner and localizer of BRCA2
|
|
260
|
0.485 |
0.769 |
3.0E-19 |
0.340 |
limited
|
1.000 |
11
|
0
|
2013 |
2019 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
O96017
|
checkpoint kinase 2
|
Kinase
|
297
|
0.460 |
0.808 |
1.2E-24 |
0.330 |
limited
|
1.000 |
14
|
0
|
2003 |
2017 |
Entrez Id: |
472 |
Gene Symbol: |
ATM |
ATM
|
Q13315
|
ATM serine/threonine kinase
|
Kinase
|
684
|
0.374 |
0.885 |
5.6E-47 |
0.330 |
moderate
|
1.000 |
9
|
0
|
2005 |
2018 |
Entrez Id: |
999 |
Gene Symbol: |
CDH1 |
CDH1
|
P12830
|
cadherin 1
|
|
508
|
0.401 |
0.808 |
0.15 |
0.320 |
limited
|
1.000 |
8
|
0
|
1998 |
2016 |
Entrez Id: |
5290 |
Gene Symbol: |
PIK3CA |
PIK3CA
|
P42336
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
|
Kinase
|
1511
|
0.292 |
0.923 |
1.00 |
0.320 |
None
|
1.000 |
2
|
0
|
2007 |
2010 |
Entrez Id: |
1027 |
Gene Symbol: |
CDKN1B |
CDKN1B
|
P46527
|
cyclin dependent kinase inhibitor 1B
|
|
454
|
0.409 |
0.769 |
0.62 |
0.300 |
limited
|
1.000 |
8
|
0
|
1998 |
2015 |
Entrez Id: |
580 |
Gene Symbol: |
BARD1 |
BARD1
|
Q99728
|
BRCA1 associated RING domain 1
|
|
75
|
0.597 |
0.538 |
1.4E-24 |
0.300 |
limited
|
1.000 |
4
|
0
|
2001 |
2016 |
Entrez Id: |
2052 |
Gene Symbol: |
EPHX1 |
EPHX1
|
P07099
|
epoxide hydrolase 1
|
|
196
|
0.500 |
0.846 |
3.2E-09 |
0.300 |
limited
|
1.000 |
3
|
0
|
1994 |
2015 |
Entrez Id: |
6224 |
Gene Symbol: |
RPS20 |
RPS20
|
P60866
|
ribosomal protein S20
|
Nucleic acid binding
|
86
|
0.610 |
0.692 |
2.1E-02 |
0.300 |
limited
|
1.000 |
2
|
0
|
2014 |
2017 |
Entrez Id: |
64218 |
Gene Symbol: |
SEMA4A |
SEMA4A
|
Q9H3S1
|
semaphorin 4A
|
Signaling
|
141
|
0.569 |
0.692 |
1.8E-05 |
0.300 |
limited
|
1.000 |
2
|
0
|
2014 |
2016 |
Entrez Id: |
6597 |
Gene Symbol: |
SMARCA4 |
SMARCA4
|
P51532
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
|
Epigenetic regulator
|
347
|
0.450 |
0.885 |
1.00 |
0.300 |
limited
|
1.000 |
2
|
0
|
2015 |
2016 |
Entrez Id: |
7518 |
Gene Symbol: |
XRCC4 |
XRCC4
|
Q13426
|
X-ray repair cross complementing 4
|
|
192
|
0.528 |
0.769 |
8.3E-07 |
0.300 |
limited
|
1.000 |
1
|
0
|
2015 |
2015 |