Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.100 None 0.988 85 1 1998 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.100 None 0.969 32 1 1996 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.100 None 0.950 20 1 1995 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.100 None 1.000 20 0 2007 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.100 None 0.947 19 0 2004 2020
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		Q13485 SMAD family member 4 Transcription factor 377 0.401 0.808 1.00 0.100 None 1.000 19 0 2001 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1087 0.320 0.885 1.4E-06 0.100 None 1.000 17 0 2007 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1105 0.319 0.885 1.00 0.100 None 1.000 16 0 2007 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1077 0.322 0.885 1.00 0.100 None 1.000 16 0 2007 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21 		microRNA 21 705 0.363 0.846 0.100 None 1.000 16 0 2010 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274 		Q9NZQ7 CD274 molecule Receptor 990 0.324 0.923 1.9E-02 0.100 None 0.917 12 0 2017 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 459 0.379 0.846 2.4E-25 0.100 None 1.000 11 1 2000 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 953 0.327 0.923 0.98 0.100 None 1.000 11 0 2010 2019
Entrez Id: 3651
Gene Symbol: PDX1
PDX1 		P52945 pancreatic and duodenal homeobox 1 105 0.530 0.654 1.8E-02 0.100 None 1.000 10 0 2004 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.090 None 1.000 9 0 2011 2019
Entrez Id: 10413
Gene Symbol: YAP1
YAP1 		P46937 Yes associated protein 1 Enzyme modulator 332 0.432 0.808 1.00 0.080 None 1.000 8 0 2006 2019
Entrez Id: 9531
Gene Symbol: BAG3
BAG3 		O95817 BAG cochaperone 3 187 0.498 0.846 0.62 0.080 None 1.000 8 0 2015 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.070 None 1.000 7 0 2009 2019
Entrez Id: 4060
Gene Symbol: LUM
LUM 		P51884 lumican 114 0.543 0.731 7.7E-02 0.070 None 1.000 7 0 2007 2019
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10 		H3 histone pseudogene 10 769 0.350 0.846 0.070 None 0.857 7 0 2002 2017
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1334 0.287 0.962 3.7E-02 0.070 None 1.000 7 0 2011 2019
Entrez Id: 7839
Gene Symbol: LEPQTL1
LEPQTL1 		Leptin, serum levels of 57 0.638 0.385 0.070 None 1.000 7 0 2013 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.070 None 0.857 7 0 2001 2018
Entrez Id: 2817
Gene Symbol: GPC1
GPC1 		P35052 glypican 1 65 0.587 0.731 1.6E-02 0.070 None 1.000 7 0 2006 2019
Entrez Id: 10232
Gene Symbol: MSLN
MSLN 		Q13421 mesothelin Extracellular structure 130 0.525 0.692 5.9E-25 0.070 None 1.000 7 0 2008 2019