Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.300 definitive 1.000 7 0 1991 2008
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.100 None 1.000 1 1 2016 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 1.000 1 6 2016 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.100 None 1.000 1 3 2016 2016
Entrez Id: 6009
Gene Symbol: RHEB
RHEB
Q15382 Ras homolog, mTORC1 binding Enzyme modulator 53 0.631 0.577 0.98 0.100 None 1.000 1 2 2016 2016
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 257 0.465 0.808 1.00 0.100 None 1.000 1 2 2016 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.100 None 1.000 1 5 2016 2016
Entrez Id: 369
Gene Symbol: ARAF
ARAF
P10398 A-Raf proto-oncogene, serine/threonine kinase Kinase 56 0.619 0.654 0.96 0.100 None 1.000 1 2 2016 2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.100 None 1.000 1 2 2016 2016
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.100 None 1.000 1 2 2016 2016
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
P22607 fibroblast growth factor receptor 3 Kinase 654 0.391 0.846 1.6E-05 0.100 None 1.000 1 2 2016 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.100 None 1.000 1 3 2016 2016
Entrez Id: 3093
Gene Symbol: UBE2K
UBE2K
P61086 ubiquitin conjugating enzyme E2 K 58 0.631 0.654 0.99 0.010 None 1.000 1 0 2011 2011
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.010 None 1.000 1 0 2011 2011
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 447 0.424 0.846 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 27338
Gene Symbol: UBE2S
UBE2S
Q16763 ubiquitin conjugating enzyme E2 S 42 0.653 0.500 0.63 0.010 None 1.000 1 0 2011 2011
Entrez Id: 997
Gene Symbol: CDC34
CDC34
P49427 cell division cycle 34 24 0.705 0.308 0.96 0.010 None 1.000 1 0 2011 2011