Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 1.000 10 0 1993 2017
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.050 None 1.000 5 0 2017 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.040 None 0.750 4 0 2009 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.040 None 0.750 4 4 2015 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.030 None 1.000 3 1 2013 2017
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.020 None 1.000 2 0 2015 2018
Entrez Id: 5443
Gene Symbol: POMC
POMC
P01189 proopiomelanocortin 873 0.356 0.846 1.2E-04 0.020 None 1.000 2 0 2019 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.020 None 1.000 2 0 2001 2008
Entrez Id: 11156
Gene Symbol: PTP4A3
PTP4A3
O75365 protein tyrosine phosphatase 4A3 106 0.566 0.654 4.5E-02 0.020 None 1.000 2 0 2008 2009
Entrez Id: 10879
Gene Symbol: SMR3B
SMR3B
P02814 submaxillary gland androgen regulated protein 3B 74 0.601 0.654 0.39 0.020 None 1.000 2 0 2008 2009
Entrez Id: 8714
Gene Symbol: ABCC3
ABCC3
O15438 ATP binding cassette subfamily C member 3 Transporter 160 0.517 0.769 1.2E-26 0.010 None 1.000 1 0 2000 2000
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
P13501 C-C motif chemokine ligand 5 Signaling 514 0.403 0.885 1.8E-03 0.010 None 1.000 1 0 2018 2018
Entrez Id: 9520
Gene Symbol: NPEPPS
NPEPPS
P55786 aminopeptidase puromycin sensitive Enzyme 172 0.519 0.808 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 634
Gene Symbol: CEACAM1
CEACAM1
P13688 CEA cell adhesion molecule 1 167 0.525 0.731 7.9E-04 0.010 None 1.000 1 0 2017 2017
Entrez Id: 6285
Gene Symbol: S100B
S100B
P04271 S100 calcium binding protein B Calcium-binding protein 599 0.383 0.923 4.4E-02 0.010 None 1.000 1 0 2013 2013
Entrez Id: 6277
Gene Symbol: S100A6
S100A6
P06703 S100 calcium binding protein A6 Calcium-binding protein 168 0.510 0.808 0.18 0.010 None 1.000 1 0 2000 2000
Entrez Id: 6185
Gene Symbol: RPN2
RPN2
P04844 ribophorin II Enzyme 33 0.686 0.462 0.11 0.010 None 1.000 1 0 2017 2017
Entrez Id: 6098
Gene Symbol: ROS1
ROS1
P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 356 0.439 0.885 1.6E-72 0.010 None < 0.001 1 0 2016 2016
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.010 None 1.000 1 0 2003 2003
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.010 None 1.000 1 0 2016 2016
Entrez Id: 57508
Gene Symbol: INTS2
INTS2
Q9H0H0 integrator complex subunit 2 85 0.590 0.654 1.00 0.010 None 1.000 1 0 1997 1997
Entrez Id: 5715
Gene Symbol: PSMD9
PSMD9
O00233 proteasome 26S subunit, non-ATPase 9 Enzyme modulator 344 0.435 0.846 4.9E-06 0.010 None 1.000 1 0 2007 2007
Entrez Id: 5627
Gene Symbol: PROS1
PROS1
P07225 protein S 283 0.467 0.846 4.7E-04 0.010 None 1.000 1 0 2017 2017
Entrez Id: 641
Gene Symbol: BLM
BLM
P54132 BLM RecQ like helicase 158 0.535 0.808 1.5E-15 0.010 None 1.000 1 0 2013 2013
Entrez Id: 65108
Gene Symbol: MARCKSL1
MARCKSL1
P49006 MARCKS like 1 169 0.508 0.731 1.4E-02 0.010 None 1.000 1 0 2000 2000