Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 47 0.460 0.808 1.2E-24 0.500 None 0.964 4 5 2002 2017
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 138 0.305 0.923 1.9E-17 0.400 None 0.967 1 0 2001 2019
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4 		P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 28 0.362 0.923 1.8E-02 0.400 None 0.967 1 0 2003 2019
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 72 0.374 0.885 5.6E-47 0.500 None 0.974 0 2 1996 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.500 None 0.975 40 13 1987 2020
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 57 0.367 0.923 9.2E-29 0.500 None 0.976 12 58 1976 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 113 0.324 0.962 1.00 0.500 None 0.978 14 5 1988 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.500 None 0.978 8 34 2004 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 141 0.291 0.885 0.56 0.400 None 0.978 3 0 1998 2019
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		Q92731 estrogen receptor 2 Nuclear receptor 73 0.400 0.923 4.5E-08 0.400 None 0.979 3 0 1999 2018
Entrez Id: 5241
Gene Symbol: PGR
PGR 		P06401 progesterone receptor Nuclear receptor 51 0.426 0.885 5.1E-02 0.400 None 0.981 2 0 1991 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.700 None 0.984 6 84 1982 2020
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 56 0.379 0.846 2.4E-25 0.500 None 0.987 3 49 1995 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 124 0.295 0.885 0.37 0.400 None 0.988 6 0 1990 2019
Entrez Id: 1440
Gene Symbol: CSF3
CSF3 		P09919 colony stimulating factor 3 168 0.377 0.885 0.38 0.320 None 1.000 8 0 1993 2018
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 96 0.344 0.923 0.89 0.400 None 1.000 6 0 1992 2019
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1 		P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 51 0.410 0.885 1.7E-05 0.400 None 1.000 5 0 1993 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.400 None 1.000 5 0 2001 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 182 0.305 0.923 0.26 0.500 None 1.000 4 6 1998 2019
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		Q14790 caspase 8 Enzyme 58 0.404 0.923 3.7E-06 0.380 None 1.000 4 0 2004 2018
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 120 0.378 0.885 8.0E-02 0.450 None 1.000 4 7 1988 2016
Entrez Id: 857
Gene Symbol: CAV1
CAV1 		Q03135 caveolin 1 Enzyme modulator 58 0.388 0.885 8.3E-03 0.400 None 1.000 4 0 1999 2017
Entrez Id: 7431
Gene Symbol: VIM
VIM 		P08670 vimentin 51 0.372 0.846 0.71 0.380 None 1.000 4 0 2003 2016
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		P04179 superoxide dismutase 2 Enzyme 285 0.379 0.923 0.15 0.400 None 1.000 4 0 2004 2010
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		P12830 cadherin 1 73 0.401 0.808 0.15 0.400 None 1.000 4 0 2002 2019