Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.440 None 0.800 5 0 2006 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.030 None 1.000 3 0 2012 2015
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1 		Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.020 None 1.000 2 0 2018 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.010 None 1.000 1 0 2014 2014
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.110 None 1.000 1 0 2008 2008
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.030 None 1.000 3 0 1998 2017
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.070 None 1.000 7 1 2001 2013
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3558
Gene Symbol: IL2
IL2 		P60568 interleukin 2 950 0.336 0.885 0.48 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.070 None 0.857 7 1 2008 2019
Entrez Id: 3952
Gene Symbol: LEP
LEP 		P41159 leptin 931 0.349 0.846 0.46 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.400 None 1.000 1 0 2017 2017
Entrez Id: 4513
Gene Symbol: COX2
COX2 		P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.120 None 1.000 2 0 2010 2018
Entrez Id: 7421
Gene Symbol: VDR
VDR 		P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.030 None 1.000 3 0 2011 2020
Entrez Id: 6696
Gene Symbol: SPP1
SPP1 		P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.120 None 1.000 2 0 2019 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.010 None 1.000 1 0 2017 2017
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.020 None 1.000 2 0 2019 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.110 None 1.000 1 0 2017 2017
Entrez Id: 847
Gene Symbol: CAT
CAT 		P04040 catalase Enzyme 794 0.359 0.962 1.6E-10 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1950
Gene Symbol: EGF
EGF 		P01133 epidermal growth factor 774 0.357 0.923 8.5E-17 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.010 None 1.000 1 0 2002 2002
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10 		H3 histone pseudogene 10 769 0.350 0.846 0.010 None 1.000 1 0 2019 2019
Entrez Id: 183
Gene Symbol: AGT
AGT 		P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.400 None 1.000 13 1 1997 2019
Entrez Id: 355
Gene Symbol: FAS
FAS 		P25445 Fas cell surface death receptor 754 0.372 0.923 0.81 0.100 None 0 0
Entrez Id: 3606
Gene Symbol: IL18
IL18 		Q14116 interleukin 18 750 0.365 0.923 3.1E-02 0.030 None 1.000 3 0 2007 2019